Nuclear organization, such as the formation of specific nuclear subdomains, is generally thought to be involved in the control of cellular phenotype; however, there are relatively few specific examples of how mammalian nuclei organize during radical changes in phenotype, such as those occurring during differentiation and growth arrest. Using human mammary epithelial cells in which growth arrest...

Radioactive agents currently available for imaging infection by gamma scintigraphy do so by identifying inflammation in response to the infection, and are therefore non-specific in so far as they are unable to distinguish between infective and non-infective inflammation. The term ‘infection imaging’ is therefore generally synonymous with ‘inflammation imaging’. This article will briefly review ...

Microtubule (MT)-based transport can be regulated through changes in organization of MT transport tracks, but the mechanisms that regulate these changes are poorly understood. In Xenopus melanophores, aggregation of pigment granules in the cell center involves their capture by the tips of MTs growing toward the cell periphery, and granule aggregation signals facilitate capture by increasing the...

Foods from agriculture and fishery products are processed using various technologies. Molecular mixture analysis during food processing has the potential to help us understand the molecular mechanisms involved, thus enabling better cooking of the analyzed foods. To date, there has been no web-based tool focusing on accumulating Nuclear Magnetic Resonance (NMR) spectra from various types of food...

Single-sided NMR devices can operate under conditions inaccessible to conventional NMR while featuring portability and the ability to analyze arbitrary-sized objects. In this paper, a semi-elliptic Halbach magnet array was designed and built for single-side Nuclear Magnetic Resonance (NMR). We present an easy-to-implement target field algorithm for single-side NMR magnet design based on Gram-Sc...

Some information about protein structure can be obtained by using Nuclear Magnetic Resonance (NMR) techniques, but they provide only a sparse set of distances between atoms in a protein. The Molecular Distance Geometry Problem (MDGP) consists in determining the three-dimensional structure of a molecule using a set of known distances between some atoms. Recently, a Branch and Prune (BP) algorith...