Early stage recognition of acral lentiginous melanoma (ALM) is important for a better prognosis, but in-depth understanding and proper management of ALM in situ is complicated, because there are only a few reports, probably due to its rarity and diagnostic difficulty. We have reviewed our experience with seven patients who were diagnosed as having ALM in situ and discuss how to accurately diagn...

Application-level multicast (ALM) is a novel technology for multipoint applications, such as large scale file distribution, video and audio streaming, and video conferencing. Although many ALM mechanisms or algorithms have been proposed, all the multicast functions have been independently developed and integrated into individual applications. In such a situation, the development of ALM applicat...

Hypocretin 1 and 2 (Hcrts; also known as orexin A and B), excitatory neuropeptides synthesized in cells located in the tuberal hypothalamus, play a central role in the control of arousal. Hcrt inputs to the locus coeruleus norepinephrine (LC NE) system and the posterior hypothalamic histaminergic tuberomammillary nuclei (TMN HA) are important efferent pathways for Hcrt-induced wakefulness. The ...

The augmented Lagrangian method (ALM) is fundamental for solving convex programming problems with linear constraints. The proximal version of ALM, which regularizes ALM’s subproblem over the primal variable at each iteration by an additional positive-definite quadratic proximal term, has been well studied in the literature. In this paper, we show that it is not necessary to employ a positive-de...

The European Union (EU) recently committed to becoming ‘the most competitive and dynamic knowledge-based economy in the world.’ Active labor market (ALM) policies are a critical part of the European Employment Strategy (EES) – the plan designed to achieve this objective. ALM policies entail several possible externalities that, spilling across national boundaries, may create incentives for Europ...

Despite the fact that global multicast is still not possible in today’s Internet, many local networks are already multicast-capable (the so-called multicast “islands”). However, most application-layer multicast (ALM) protocols for streaming have not taken advantage of the underlying IP multicast capability. As IP multicast is more efficient, it would be beneficial if ALM can take advantage of s...

In this paper, we propose an Adaptive Lattice Model (ALM) for simplifying linear features of geographic data. An ALM, based on spatial constraints or the target resolution of the data to be created, represents spatial data by latticing adaptively the spatial space at the target resolution and omitting all details smaller or finer than the resolution. Out of two implementations of ALM, this pape...

Application-level multicast (ALM) is being increasingly recognized as a solution to support multipoint applications without the need for a network layer multicast protocol. Though several ALM systems have been proposed, all the multicast functions are independently developed and integrated into individual applications. However, we can find out the common functions of ALM among the existing syst...

     The goal of this study was to prepare and characterize alginate microspheres as an antigen delivery system and adjuvant for immunization against leishmaniasis. Microspheres encapsulated with autoclaved Leishmania major (ALM) and Quillaja saponin (QS) were prepared by an emulsification technique and characterized for size, encapsulation efficiency and release profile of encapsulate...

We define a RELOAD Usage for Application Layer Multicast as well as a mapping to the RELOAD experimental message type to support ALM. The ALM Usage is intended to support a variety of ALM control algorithms in an overlay-independent way. Two example algorithms are defined, based on Scribe and P2PCast. Internet-Drafts are draft documents valid for a maximum of six months and may be updated, repl...