نتایج جستجو برای: alloimmunization
تعداد نتایج: 866 فیلتر نتایج به سال:
OBJECTIVE The aim of this study was to analyze the alloimmunization against red blood cells (RBC) among Kuwaiti population. MATERIALS AND METHODS Retrospective analysis of RBC alloimmunization among 179,045 Kuwaiti patients, pregnant women, and allogeneic blood donors was conducted for the period of 1992-2001. The frequency of 24 alloantibody specificities from 1,278 alloimmunized Kuwaitis wa...
Randomized controlled trials have shown a reduction in platelet alloimmunization and refractoriness in patients with acute leukemia (AL) with the use of poststorage leukoreduction of blood products. Universal prestorage leukoreduction (ULR) of red cell and platelet products has been performed in Canada since August 1999. We conducted a retrospective analysis of 13 902 platelet transfusions in 6...
Background and purpose: Ïncreasing transfusion need is one of the main problems in thalassemic pathients. Âlloimmunization is one of the most complicated causes of this problem which is an immunologic response to foreign antigens. Âccording to different studies, its frequency is 5% to 21% in major B-thalassemic patients. Âlloimmunization leads to decrease RBÇs life span, an so, demands for in...
Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious complications for the patient including life-threatening delayed hemolytic transfusion reactions and difficulty in finding compatible units, which can cause transfusion delays. In this review, we discuss the risk fac...
Red blood cell (RBC) alloimmunization occurs in approximately 30% of transfused sickle cell disease patients compared to 2-5% of all transfusion recipients. Because RBC transfusion is an important part of therapy in sickle cell disease, the need for additional antigen matching once alloimmunization occurs is problematic and leads to therapeutic limitations. Thus, identification of risk factors ...
life-long red blood transfusion remains the main treatment for severe thalassemia. the development of hemolytic alloantibodies and erythrocyte autoantibodies complicated transfusion therapy in thalassemia patients. the frequency causes and prevention of this phenomenon among 80 transfused thalassemia patients were evaluated in ali asghar children's hospital during 1998-2004 in a cross-sectional...
1. Lee S. The value of DNA analysis for antigens of the Kell and Kx blood group systems. Transfusion 2007;47:32S-39S. 2. Aygun B, Padmanabhan S, Paley C, Chandrasekaran V. Clinical significance of RBC alloantibodies and autoantibodies in sickle cell patients who received transfusions. Transfusion 2002;42:37-43. 3. Castro O, Sandler SG, Houston-Yu P, Rana S. Predicting the effect of transfusing ...
BACKGROUND Infections, particularly those caused by invasive fungi, are a major cause of death in patients with severe aplastic anemia. The purpose of this study was to analyze our experience with granulocyte transfusions in such patients. DESIGN AND METHODS A retrospective analysis was performed on all patients with severe aplastic anemia who had received granulocyte transfusions between 199...
OBJECTIVE To provide guidelines on use of anti-D prophylaxis to optimize prevention of rhesus (Rh) alloimmunization in Canadian women. OUTCOMES Decreased incidence of Rh alloimmunization and minimized practice variation with regards to immunoprophylaxis strategies. EVIDENCE The Cochrane Library and MEDLINE were searched for English-language articles from 1968 to 2001, relating to the preven...
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