Carbodiimide reacts with isocyanide catalyzed by copper(i) iodide, leading to benzoimidazo[1,5-a]imidazoles in good yields. This reaction is efficient, and proceeds through a formal [3+2] cycloaddition and C-N coupling.

The anion binding affinity of a macrocyclic Rh complex can be allosterically regulated by reaction with a small molecule (an isocyanide), which effects a change in macrocycle size and shape.

The activation of carbon dioxide, organonitriles, and terminal acetylenes by (boryl)iminomethanes derived from isocyanide 1,1-hydroboration is described. Also detailed is the generality of hydroboration of m-terphenylisocyanides with hydroboranes of differing Lewis acidities.

An unprecedented silver-catalyzed cascade reaction of tosylmethyl isocyanide (TosMIC) with propargylic alcohols for the efficient synthesis of (E)-vinyl sulfones has been developed where TosMIC plays a dual role as both the reactant in the allenylation of propargylic alcohols and the sulfonyl source.

We report here the synthesis and characterization of a family of copper(I) metal precursors based around cyclopentadienyl and isocyanide ligands. The molecular structures of several cyclopentadienylcopper(I) isocyanide complexes have been unambiguously determined by single-crystal X-ray diffraction analysis. Thermogravimetric analysis of the complexes highlighted the isopropyl isocyanide comple...

The potential energy surfaces of acetyl cyanide and its functional isomer acetyl isocyanide in their electronic ground state have been investigated using ab initio molecular orbital MP2(FU)/6-311G** and QCISD(T)/6311G** calculations. The molecular eliminations of CH3COX (X ) CN,NC) to CH3X + CO, HX + CH2CO, and CH2 + HCOX, the unimolecular rearrangements to CH3C-OX and CH3O-CX carbenes, 1,3-hyd...

the synthesis of aryl amides via the reactions of carboxylic acids and isocyanides in methanol was carried out in 78-95% yields under ultrasound irradiation. the method has wide applicability, and the protocol is mild, fast and efficient compared to the existing methods based on silent conditions.

Invited for this month's cover is the group of Karol Grela (University of Warsaw) in collaboration with Apeiron Synthesis (based in the Wrocław Technology Park). The researchers created a new, bidentate isocyanide scavenger that is very effective at removing ruthenium residues from the products of olefin metathesis. The Full Paper itself is available at 10.1002/cssc.201500784.