There is a wide difference of opinion regarding the criteria necessary for the diagnosis of haemorrhagic disease of the newborn. Formerly, the essential feature seems to have been bleeding from the alimentary tract, hence the synonym 'melaena neonatorum.' More recently a wider view has been taken and many authorities do not consider that haemorrhage into the alimentary tract is necessary for di...

The metabolism and binding of the volatile carcinogen 1,2-dibromo[14C]ethane (DBE) were studied in C57BL mice, Sprague-Dawley rats, and Fischer rats. As shown by the whole-body and light microscopic autoradiography with heated and/or extracted sections, a selective accumulation of metabolites occurred in a number of tissues, preferentially in the reported target tissues for DBE-induced lesions ...