نتایج جستجو برای: ali rafiee

تعداد نتایج: 9454  

Journal: :American Journal of Islam and Society 2016

Journal: :American journal of respiratory cell and molecular biology 2006
Li Gao Audrey Grant Indrani Halder Roy Brower Jonathan Sevransky James P Maloney Marc Moss Carl Shanholtz Charles R Yates Gianfranco Umberto Meduri Mark D Shriver Roxann Ingersoll Alan F Scott Terri H Beaty Jaideep Moitra Shwu Fan Ma Shui Q Ye Kathleen C Barnes Joe G N Garcia

The genetic basis of acute lung injury (ALI) is poorly understood. The myosin light chain kinase (MYLK) gene encodes the nonmuscle myosin light chain kinase isoform, a multifunctional protein involved in the inflammatory response (apoptosis, vascular permeability, leukocyte diapedesis). To examine MYLK as a novel candidate gene in sepsis-associated ALI, we sequenced exons, exon-intron boundarie...

Journal: :Physiological genomics 2009
Judie A Howrylak Tamas Dolinay Lorrie Lucht Zhaoxi Wang David C Christiani Jigme M Sethi Eric P Xing Michael P Donahoe Augustine M K Choi

The acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) was described 30 yr ago, yet making a definitive diagnosis remains difficult. The identification of biomarkers obtained from peripheral blood could provide additional noninvasive means for diagnosis. To identify gene expression profiles that may be used to classify patients with ALI, 13 patients with ALI + sepsis and 20 pati...

Journal: :Critical Care 2006
Sanjay Manocha Anthony C Gordon Ebrahim Salehifar Horacio Groshaus Keith R Walley James A Russell

INTRODUCTION Beta2 agonists have several properties that could be beneficial in acute lung injury (ALI). We therefore chose to study the effect of inhaled beta2 agonist use (salbutamol) on duration and severity of ALI. METHODS We undertook a retrospective chart review of 86 consecutive mechanically ventilated patients with ALI, who had varying exposure to inhaled salbutamol. The cohort was di...

2011
John J Arcaroli Nianjun Liu Nengjun Yi Edward Abraham

INTRODUCTION Our purpose was to investigate variation within the IL-32 promoter and gene, and susceptibility to and outcomes from infection associated acute lung injury (ALI). METHODS Retrospective case-control study involving healthy individuals (controls) and patients (cases) with infection-associated ALI. Two hundred fifty-eight healthy normal controls and 251 patients with infection-assoc...

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015
Hong Bao Fengying Gao Guogang Xie Zhenwei Liu

BACKGROUND/AIMS Angiotensin converting enzyme 2 (ACE2) treatment suppresses the severity of acute lung injury (ALI). The effects of ACE2 in ALI have been shown to not only result from its antagonizing hydrolyzing angiotensin II (AngII), which is responsible for reduction in the vascular tension and pulmonary accumulation of inflammatory cells, but also result from a role of ACE2 in suppressing ...

2017
Masaki Tomita Takanori Ayabe Ryo Maeda Kunihide Nakamura

Background Previous study of ours showed that advanced lung cancer inflammation index (ALI) and C-reactive protein (CRP) are independent significant prognostic factors in operable non-small cell lung cancer (NSCLC) patients. Since both ALI and CRP are markers of inflammation, the aim of this study was to examine whether the combination of ALI and CRP is a prognostic indicator of resected NSCLC ...

2017
Xiao-Guang Lu Xin Kang Li-Bin Zhan Li-Min Kang Zhi-Wei Fan Li-Zhi Bai

AIM To identify circulating micro (mi)RNAs as biological markers for prediction of severe acute pancreatitis (SAP) with acute lung injury (ALI). METHODS Twenty-four serum samples were respectively collected and classified as SAP associated with ALI and SAP without ALI, and the miRNA expression profiles were determined by microarray analysis. These miRNAs were validated by quantitative reverse t...

2010
Chong Hong Yee Shigehisa Aoki Kazuyoshi Uchihashi Aki Matsunobu Fumio Yamasaki Noriyuki Misago Meihua Piao Uemura Tetsuji Nobuhisa Yonemitsu Hajime Sugihara Shuji Toda

The air-liquid interface (ALI) is a common microenvironment of the skin, but it is unknown whether the ALI affects melanoma cell behaviors. Using a collagen gel invasion assay, immunohistochemistry, and Western blots, here we show that melanoma cell proliferation in cultures with an ALI is higher than melanoma cell proliferation in submerged cultures. Bromodeoxyuridine (BrdU) uptake, an indicat...

Journal: :Translational research : the journal of laboratory and clinical medicine 2016
Cong-Lin Liu Yi Wang Mengyang Liao Marcela M Santos Cleverson Fernandes Galina K Sukhova Jin-Ying Zhang Xiang Cheng Chongzhe Yang Xiaozhu Huang Bruce Levy Peter Libby Gongxiong Wu Guo-Ping Shi

Inflammation drives asthma and atherosclerosis. Clinical studies suggest that asthmatic patients have a high risk of atherosclerosis. Yet this hypothesis remains uncertain, given that Th2 imbalance causes asthma whereas Th1 immunity promotes atherosclerosis. In this study, chronic allergic lung inflammation (ALI) was induced in mice by ovalbumin sensitization and challenge. Acute ALI was induce...

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