Sulforaphane (1-isothiocyanate-4-methyl sulfonyl butane) is a plant extract (obtained from cruciferous vegetables, such as broccoli and cabbage) and is known to exert anticancer, antioxidant and anti-inflammatory effects. It stimulates the generation of human or animal cells, which is beneficial to the body. The aim of the current study was to determine whether sulforaphane protects against lip...

Acute lung injury (ALI) is an inflammatory lung disease that manifests itself in patients as acute respiratory distress syndrome and thereby contributes significantly to the morbidity and mortality of patients experiencing critical illness. Even though it may seem counterintuitive, as the lungs are typically well-oxygenated organs, hypoxia signaling pathways have recently been implicated in the...

Landsat Thematic Mapper (TM) data and spectral mixture analysis have been used to estimate vegetation green cover in the Great Basin, western United States, to 4.0% green cover (%GC). In this paper, we compare estimates of percent green cover derived from EO-1 Advanced Land Imager (ALI) data to estimates derived from field-based analyses and to results derived from Landsat Enhanced Thematic Map...

This a rare case of adenoid hypertrophy in a 23 years old Saudi non-smoker female, who presented with severe bilateral nasal obstruction, mouth breathing, anterior nasal discharge, snoring for the last 7 months. The nasopharynx was examined by flexible nasopharyngoscope, which showed a big mass occupying the nasopharynx. Under general anesthesia, adenoidectomy was performed. Immediately after t...

Green incentives are included in the “American Recovery and Reinvestment Act of 2009” (ARRA). It is, however, unclear how these government incentives can be carried out most effectively according to market-based principles and if they can serve as a catalyst for an accelerated green transformation and an ultimate solution to the current U.S. and global economic and financial crisis. The article...

Various types of motion and deformation the lung undergoes during minimally invasive tumor ablative procedures, e.g. Low Dose Rate (LDR) brachytherapy, have been investigated and modeled in this dissertation. Modeling such motions and deformations are highly necessary for enhancing the accuracy of lung’s Minimally Invasive Surgery (MIS). This necessity stems from the fact that due to its porous...

The use of biomarkers to refine patient populations, such that clinical trials will be most likely to provide a definitive answer requiring the fewest patients, is particularly appealing for application to research involving patients with a heterogeneous syndrome like ALI/ARDS. This could be beneficial by helping to characterize either a group of patients with a high mortality where mortality i...

BACKGROUND It is unclear whether an "obesity paradox" exists in the respiratory system, especially in acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). Previous studies have postulated a causal relation between obesity and ARDS/ALI but have lacked power to form a definitive conclusion. OBJECTIVE To investigate the relationships between obesity, ARDS/ALIrisk, and mortalit...

OBJECTIVE Neutrophils are an important component of the inflammatory response that characterizes acute lung injury (ALI). This discussion aims to review the contribution of neutrophils to the development and progression of ALI and to highlight the major intracellular signaling pathways that are involved in neutrophil activation in the setting of ALI. DATA SOURCES MEDLINE, original research pa...

In this review we summarize recent major advances in our understanding on the molecular mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary barrier dysfunction, highlighting the role of immune cells, inflammatory and noninflammatory signaling events, mechanical noxae, and the affected cellular and molecular entities and functions. Furthermore, we address nove...