BACKGROUND This study examined whether the experiences of childhood or adolescent parental divorce/separation and parental alcohol problems affected the likelihood of offspring DSM-IV lifetime alcohol dependence, controlling for parental history of drug, depression, and antisocial behavior problems. METHOD Data were drawn from the 2001-2002 National Epidemiological Survey on Alcohol and Relat...

Alcohol dependence is a chronically relapsing disorder characterized by compulsive drug seeking and drug taking, loss of control in limiting intake, and the emergence of a withdrawal syndrome in the absence of the drug. Accumulating evidence suggests an important role for synaptic transmission in the central amygdala (CeA) in mediating alcohol-related behaviors and neuroadaptative mechanisms as...

background: this review was performed to evaluate the trend of alcohol use, characteristics of consumers, alcohol use disorders and toxic alcohol intoxications in bangladesh. in addition, sources and sales figures of alcoholic beverages, and number of legal permits issued for alcohol consumption are reported and analyzed. methods: a narrative search was performed on available medical literature...

BACKGROUND To study the relationship between alcohol abuse or dependence as diagnosed by the CAGE questionnaire, and nicotine dependence as diagnosed by Fagerström Test of Nicotine Dependence (FTND) in French seamen. MATERIALS AND METHODS French seamen were recruited from a stratified survey of 19 ports in France. The subjects completed a questionnaire during their annual medical check-up wit...

This purpose of this study is to provide basic data for treatment by analyzing the characteristics of patients with alcohol dependence and the relationship between depression and alcohol dependence. The subjects were 44 patients with alcohol dependence aged 20-70 in a psychiatric hospital. Alcohol Dependence Scale(ADS) and Beck Depression Inventory(BDI) were used as measuring tools. The collect...

Abstract Introduction Concurrent alcohol dependence poses a significant burden to health and wellbeing of people with established opioid dependence. Although previous research indicates that both genetic and environmental risk factors contribute to the development of drug or alcohol dependence, the role of genetic determinants in development of concurrent alcohol and opioid dependence has not b...

Animal models are important tools in the study of alcohol use, abuse, and dependence because they allow researchers to use methods that cannot be used with human subjects. Animal models have been developed to study various aspects of alcohol use and dependence, including alcohol-seeking behavior, alcohol-related organ damage, tolerance to alcohol, and physical dependence on alcohol. Because ani...

BACKGROUND Alcohol dependence is one of the leading causes of the global burden of disease. Among members of the Uganda Police Force, alcohol dependence has been a major contributor of poor mental health, poor work output and forced retirement. OBJECTIVE This study was carried out to determine the prevalence of alcohol dependence and associated psychosocial problems in the Uganda Police Force...

The alcohol dependence syndrome includes the presence of alcohol tolerance, physical dependence and an inability to control one's alcohol intake. Studies are reviewed that implicate the mesolimbic dopaminergic systems, and the y-aminobutyric acid-A (GABAA) and A'-methyl-D-aspartate (NMDA) receptors as mediators of various aspects of the alcohol dependence syndrome. It is suggested that alcohol-...

Alcohol dependence is characterized by frequent, compulsive and uncontrolled consumption of alcohol associated with behavior of maladaption and destruction. It is an etiologically and clinically heterogeneous syndrome, moderately to highly heritable, and caused by interaction of genes and environment. Alcohol dependence is related to other psychiatric diseases by common neurobiological pathways...