Introduction: Exposure to ionizing radiation can trigger adverse biological effects on healthy tissues, such as causing hematological toxicity and potential injury to different organs. Ionizing radiation has sufficient energy to liberate electrons from atoms leaving them with unpaired electrons; hence ionizing them and producing free radicals. In the current study, the...

the aim of this study was to evaluate antitumour activity of the roots of hibiscus tiliaceus linn. against dalton’s ascitic lymphoma (dal) in swiss albino mice. a significant enhancement of mean survival time (mst) of h. tiliaceus treated tumour bearing mice was found with respect to control group. h. tiliaceus treatment was found to enhance peritoneal cell counts. when these h. tiliaceus treat...

Background: Polygonum bistorta has been used as a remedy for jaundice, smallpox, pimples, measles, cholera, diarrhoea, dysentery, expelling worms, insect stings and snakebites. In this study, the crude extract from P. two fractions viz. hexane chloroform obtained were studied their median Lethal Dosages (LD50) in Swiss albino mice. Methods: Powdered rhizomes of was macerated with dissolved solv...

This study has revealed significant variation in total ATPase activity after administration of aluminium acetate in different tissues of albino mice. With sublethal dose (3.5 mg/kg body weight) of aluminium acetate, total ATPase activity was decreased in brain (-50.61), liver (-50.69), kidney (-30.74), heart (-64.07), muscle (-51.50) and testis (-65.53) of albino mice. The decrement was enhance...

A 14-day subchronic genotoxicity of Nimesulide was evaluated by employing mouse bone marrow chromosomal aberration test. The Nimesulide administered orally for 2 weeks at the rate of 1.5, 2.5, 5 mg/kg body weight in swiss albino mice. The results show decreased mitotic activity in all groups of Nimesulide treatments. Similar results concerning the chromosomal aberrations revealed in all treated...

the methanolic extracts of indigofera aspalathoides (meia) and wedelia calendulaceae (mewc) were evaluated for their anticancer activity against ehrlich ascites carcinoma (eac) in swiss albino mice. on day 1, the extract of indigofera aspalathoides at a dose of 250 and 500 mg/kg body weight and the extract of wedelia calendulaceae at a dose of 250 and 500 mg/kg body weight were administered ora...

The acute toxicity of hexavalent chromium as potassium dichromate (K2Cr2O7) was studied in female albino mice. Reproductive parameters in ovary and uterus and fertility rate were evaluated to investigate the possible effects of chromium intoxication. Seventy-five adult albino mice were used in this study.The mice treated orally with 500 and 1000 ppm of potassium dichromate that dissolved in tap...