Runx3, a member of Runt-related transcription factor (Runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. In the present study, exogenous Run3 was transiently expressed in AGS (human gastric adenocarcinoma), with undetectable Runx3 protein and in A549 (human lung carc...

Abs confer protection from secondary infection with Legionella pneumophila, the causative agent of a severe form of pneumonia known as Legionnaires' disease. In this study, we demonstrate that Ab-mediated protection is effective across L. pneumophila serogroups, suggesting that Abs specific for conserved protein Ags are sufficient to mediate this protective effect. We used two independent metho...

Various big-data analytics tools and techniques have been developed for handling massive amounts of data in the healthcare sector. However, scheduling is a significant problem to be solved smart applications provide better quality services improve efficiency related processes when considering large medical files. For this purpose, new hybrid model called Gaussian Relevance Vector MapReduce-base...

Polyvalent mosaic HIV immunogens offer a potential solution for generating vaccines that can elicit immune responses against genetically diverse viruses. However, it is unclear whether key T cell epitopes can be processed and presented from these synthetic Ags and recognized by epitope-specific human T cells. In this study, we tested the ability of mosaic HIV immunogens expressed by recombinant...

Runx3, a member of Runt-related transcription factor (Runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. In the present study, exogenous Run3 was transiently expressed in AGS (human gastric adenocarcinoma), with undetectable Runx3 protein and in A549 (human lung carc...

Linear increases in G tolerance with increases in anti-G suit (AGS) bladder inflation pressure occurred when relaxed subjects were exposed to acceleration plateaus while riding a centrifuge and were either seated upright, (15 degrees seat back angle or SBA) or supine (60 degrees SBA). Supine G tolerance with AGS bladder inflation decreased as G onset time was increased by factors of two and fou...

Secreted or nonsecreted Ag expressed by recombinant Listeria monocytogenes can prime CD8 T cells. However, Ag-specific memory CD8 T cells confer protection against bacteria secreting Ag, but not against bacteria expressing the nonsecreted form of the same Ag. This dichotomy may be explained by a long-standing hypothesis that nonsecreted Ags are less effective than secreted Ags at inducing a pro...

Aerobic granular sludge (AGS) is a recent innovative technology and considered forthcoming biological process for sustainable wastewater treatment. AGS composed of the dense microbial consortium aerobic, anaerobic, facultative types bacteria. The mechanism formation its stability long-term operation still subject current research. On other hand, makes treatment in cost-effective way. However, o...