Objective. To explore whether GC (group-specific component) rs17467825, rs4588, and rs7041 polymorphisms are associated with generalized aggressive periodontitis. Methods. This case-control study recruited 372 patients with generalized aggressive periodontitis (group AgP) and 133 periodontal healthy subjects (group HP). GC rs17467825, rs4588, and rs7041 genotypes and plasmatic vitamin D-binding...

INTRODUCTION Understanding the changes in bone density of patients affected by aggressive periodontitis could be useful in early disease detection and proper treatment planning. AIM The aim of this study was to compare alveolar bone density in patients affected with aggressive periodontitis and periodontally healthy individuals using Cone Beam Computed Tomography (CBCT). MATERIALS AND METHO...

INTERLEUKIN-6 LEVELS IN GENERALIZED AND LOCALIZED AGGRESSIVE PERIODONTITIS PATIENTS By Bindu Reddy, D.D.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at the Virginia Commonwealth University Virginia Commonwealth University, 2004 Major Director: Joseph V. Califano, D.D.S., Ph.D. Associate Professor, Department of Periodontics Periodontitis i...

BACKGROUND Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is found in periodontitis lesions and its presence in subgingival plaque significantly increases the risk for periodontitis. We have previously shown that patients with aggressive forms of periodontitis that are seropositive for P. gingivalis have less attachment loss than those that are seronegative. This suggests ...

Periodontal diseases are among the most frequent diseases affecting children and adolescents. These include gingivitis, localized or generalized aggressive periodontitis (a.k.a., early onset periodontitis) and periodontal diseases associated with systemic disorders. The effects of periodontal diseases observed in adults have earlier inception in life period. Gingival diseases in a child may pro...

AIM The aim of this study is to investigate the effect various dietary nutrients in aggressive periodontitis patients. MATERIALS AND METHODS A total of 85 patients were selected and divided into two groups, 45 patients are with aggressive periodontitis and 40 patients are healthy. Periodontal parameters such as oral hygiene index, Russels periodontal index and radiograph were taken. The food ...

background and aims. mast cells play an important role in allergic reactions, host defense, local homeostasis, inflammation and angiogenesis. the aim of this study was to evaluate the relationship between mast cell counts and different types of periodontitis. materials and methods. gingival specimens were taken from 20 moderate-to-advanced chronic and 19 moderate-to-advanced aggressive periodon...

Recent studies indicate a mutual epidemiological relationship between coronary heart disease (CHD) and periodontitis. Both diseases are associated with similar risk factors and are characterized by a chronic inflammatory process. In a candidate-gene association study, we identify an association of a genetic susceptibility locus shared by both diseases. We confirm the known association of two ne...

OBJECTIVE Based on the evidence regarding the relationship between inflammatory processes and stress responses, the present study investigated the association between psychological stress and elevation of inflammatory mediators related to periodontal disease in adult patients. MATERIALS AND METHODS The study consisted of 50 patients including 25 patients with chronic periodontitis and 25 case...

AIM These case series were aimed at highlighting late presentations of aggressive periodontitis (AP) in a teaching hospital as well as proffering possible reasons for such presentations which would serve as part of the solution to prevent such presentations in the future. BACKGROUND Aggressive periodontitis is a severe form of destructive periodontitis traditionally believed to present around...