UNLABELLED BACKGROUND Early life-stage exposure to estrogen increases the risk of breast cancer. The objective of this study was to investigate the age at menarche and time to onset of regular menstrual cycles for Japanese women born between 1930 and 1985. METHODS A cross-sectional study was designed using data from the baseline survey of the Japan Nurses' Health Study. The data from 48,10...

This study examines the differences between young and old adult voices. Acoustic cues in voices that enable listeners to recognize a speaker’s vocal age are specified as well as acoustic cues that straightly indicate the speaker’s chronological age. Electroglottographic data were used to directly examine glottal behaviour in aging voices. We found a strong spectral attenuation of high frequenci...

Background and Purpose: Patients with Bipolar I Disorder recurrence experiences mood variation between manic and depression during the time. Hence, that is need to the longitudinal study on Bipolar Disorder patients. This study aims to evaluate the effective factors on Bipolar I Disorder frequent recurrence in 5 years longitudinal study using generalized estimation equations (GEE) m...

Epilepsy in older individuals has an elevated incidence. The objective of the present work was to evaluate the clinical, EEG and brain imaging aspects in patients showing late-onset epilepsy. Fifty-five patients with late-onset epilepsy (older than 50 years) were evaluated. They were composed of two groups according to the onset age of the epilepsy seizure (ES): 51-60 (G51-60) and over 60 (G60+...

The ability of kittens (45-135 days of age) to segment images based on textural differences was examined using a two-alternative forced-choice procedure on the jumping stand. Tasks based on 3 textural cues--element size, element density and element orientation--were presented concurrently in a within-subject design. Texture segmentation based on element size appeared as early as 47 days of age,...