AGC kinases are important regulators of cell growth, metabolism, division, and survival in mammalian systems. Mutation or deregulation of members of this family of protein kinases contribute to the pathogenesis of many human diseases, including cancer and diabetes. Although AGC kinases are conserved in the plant kingdom, little is known about their molecular functions and targets. Some of the b...

OBJECTIVES To determine how human papillomavirus (HPV) positivity of atypical glandular cells (AGCs) affects the predictive values for the presence of high-grade cervical lesions. DESIGN Population-based cohort study. SETTING Stockholm-Gotland region, Sweden. PARTICIPANTS Between 17 February 2014 and 30 June 2016, there were 562 women with AGC detected in a cervical sample. Registry linka...

The purpose of this study was to determine the effect of a nonuniform coating, abluminal-gradient coating (AGC), which leaves the abluminal surface of the curves and links parts of the stent free from the drug coating, on the diffusion direction of the drug and the biological responses of the artery to drug-eluting stent (DES) by comparing the AGC-sirolimus stent and the conventional full-surfa...

A high performance automatic gain control (AGC) circuit of analog type is presented in this paper. The proposed AGC incorporates a modified sample and hold peak-detector. Circuit operations of this new peak-detector are demonstrated superior to the conventional one, by both keeping and tracking the peak of the input signal at the same time. Furthermore, the design complexity of the proposed AGC...

43 ABSTRACT An optimal fuzzy AGC regulator design based on GASA tuning technique for interconnected power system is proposed in this paper. The investigations with the GASA tuned optimal fuzzy regulator are carried out on a two area interconnected power system consisting of power plants with different characteristics. Power system area-1 is having plants with reheat thermal turbines whereas are...

The purpose of this study was to investigate the accuracy of double contrast-enhanced ultrasonography (DCEUS) for assessing the Borrmann classification of advanced gastric carcinoma (AGC) preoperatively. Three hundred twenty nine patients with proved AGC were enrolled. DCEUS (intravenous microbubbles combined with combined with oral contrast-enhanced ultrasound) was performed preoperatively. Th...

More than 100,000 publications demonstrate that AGC kinases are important regulators of growth, metabolism, proliferation, cell divison, survival and apoptosis in mammalian systems. Mutation and/or dysregulation of these kinases contribute to the pathogenesis of many human diseases, including cancer and diabetes. Although AGC kinases are also present in plants, little is known about their funct...

Expansion of (AGC)n repeats has been associated with genetic disorders called triplet-repeat diseases such as Huntington's disease (HD), myotonic muscular dystrophy (DM) and Kennedy's disease. To gain insight into the abnormal behavior of these repeats, we studied their structural properties in supercoiled DNA. Chemical probing revealed that, under physiological salt and pH conditions, Zn2+ or ...

Early diagnosis of Borrmann type 4 advanced gastric cancer (AGC) is very important for improving the prognosis of AGC patients. Because there is no definite mass in most cases of Borrmann type 4 AGC, its accurate diagnosis via endoscopy requires an understanding of its pathogenesis and developmental process. Moreover, many people confuse linitis plastica (LP) type gastric cancer (GC), scirrhous...

Automatic generation control (AGC) is primarily responsible for ensuring the smooth and efficient operation of an electric power system. The main goal AGC to keep operating frequency under prescribed limits maintain interchange at intended level. Therefore, system must be supplemented with modern intelligent techniques provide adequate supply. This paper provides a comprehensive overview variou...