Post-translational modification of Ras proteins includes prenylcysteine-directed carboxyl methylation. Because Ras participates in Erk activation by epidermal growth factor (EGF), we tested whether Ras methylation regulates Erk activation. EGF stimulation of Erk was inhibited by AFC (N-acetyl-S-farnesyl-L-cysteine), an inhibitor of methylation, but not AGC (N-acetyl-S-geranyl-L-cysteine), an in...

Oocytes isolated from cows of reproductive age with reduced antral follicle counts (AFC) have a diminished capacity of embryonic development, which may be related to alterations in the mechanism that directs the proper segregation of chromosomes. Because we demonstrated that progesterone receptor membrane component 1 (PGRMC1) is involved in chromosome congression and metaphase II (MII) plate fo...

Animal temperament is a trait of economic relevance and its use as a selection criterion requires the identification of environmental factors that influence this trait, as well as the estimation of its genetic variability and interrelationship with other traits. The objectives of this study were to evaluate the effect of the covariates dam age at calving (ADC), long yearling age (YA) and long y...

Data on production performance of 200 animals maintained at University Livestock Farm, Kerala Agricultural University, Mannuthy and Cattle Breeding Farm, Thumburmuzhi were used for the study. Among the eight economically important traits [305 day milk yield, fat percentage, protein percentage, SNF(Solids not fat), total solids, peak yield, days to attain peak yield and AFC(Age at first calving)...

A light-storage experiment with a total (storage and retrieval) efficiency η=56% is carried out by enclosing a sample, with a single-pass absorption of 10%, in an impedance-matched cavity. The experiment is carried out using the atomic frequency comb (AFC) technique in a praseodymium-doped crystal (0.05%Pr(3+):Y2SiO5) and the cavity is created by depositing reflection coatings directly onto the...

This paper presents concurrent vibration control of a laboratory scaled vibration isolator platform with Active Force Control (AFC) using Iterative Learning Algorithm (ILA). The work investigates the performance of the traditional Proportional Integral Derivative Controller (PIDC) with and without AFC using ILA for vibration suppression. The physical single degree of freedom quarter car has bee...

Background Sustainable public transport is not an option; it is a necessity [1]. In a media competition run by the Institution of Engineering and Technology (IET), we introduced an award-winning design model of financially secure and sustainable automatic fare collection (AFC) [2]. In the public transport industry, AFC commonly refers to transit providers’ automated ticketing systems for collec...

Recent studies indicate that the antral follicle population may be of paramount importance to improve reproductive performance in cows. There is already an agreement that the antral follicle count (AFC; follicles ≥3 mm in diameter) is a highly variable trait among animals, but with high repeatability in the same individual. Thus, females can be classified into low, intermediate or high AFC. Sev...

Among all the available approaches for software piracy forensics, one existing and exceptional approach is the theoretical frame work called AFC (Abstraction-Filtering-Comparison), an accepted approach in US courts for evaluating copyright infringement claims involving computer software. Through this paper, the authors would like to approach AFC in a threefold manner: One, to discuss the nature...