OBJECTIVES This study was designed to compare the levels of dityrosine-containing protein cross-link products, also known as advanced oxidation protein products (AOPP); in patients with allergic rhinitis with those in healthy individuals considering the fact that AOPP has the potential to be a marker of oxidative stress specific to proteins in mammalian systems. PATIENTS AND METHODS This stud...

Previous studies have indicated that the main molecular characteristic of aging is the progressive accumulation of oxidative damages in cellular macromolecules. Proteins are one of the main molecular targets of age-related oxidative stress, which have been observed during aging process in cellular systems.. Reactive oxygen species (ROS) can lead to oxidation of amino acid side chains, formation...

OBJECTS The aim of this study is to evaluate protein oxidation, DNA damage, and lipid peroxidation in patients with gastric cancer and to investigate the relationship between oxidative stress and gastric cancer. METHODS We investigated changes in serum protein carbonyl (PC), advanced oxidation protein products (AOPP), and 3-nitrotyrosine (3-NT) levels, as indicators of protein oxidation, seru...

       In this study, we examined the antioxidant activities of methanolic extract of three endemic species of Salvia from Iran (S. lachno...

BACKGROUND Polycystic ovary syndrome (PCOS) is a common disorder of infertility which affects more than 100 million women. It is characterized by chronic anovulation, hyper androgenism and obesity. PCOS is also associated with oxidative stress changes. OBJECTIVE Here, we aimed to investigate the level of antioxidants and oxidative stress in Iranian women with PCOS as a predictive factor for c...

BACKGROUND Advanced glycation endproducts (AGE) and advanced oxidation protein products (AOPP) play a pivotal role in the development of diabetes associated diseases. The herbal medicines Padma 28 and Padma Circosan have shown effectiveness in symptoms of diabetes associated diseases and have antioxidant effects. It is not known whether inhibition of AGE and AOPP formation is a mechanism of the...