conclusions this intervention offers a practical approach for treatment of patients with nafld with diet therapy. patients and methods forty four patients with nafld received a diet including a 500 to 1000 kcal per day intake reduction as30% fat, 15% protein, and 55% carbohydrate for six months. anthropometric parameters, alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma g...

Abstract Background The 3-years mortality rate in patients with Type 2 diabetes (T2D) after minor amputations may reach 53–80%. aim of the study was to evaluate impact persistent medication adherence and compliance lifestyle recommendations on 1-year all-cause T2D peripheral artery disease (PAD) foot amputation. Methods This is a prospective, single-center, observational cohort including 785 co...

Three-dimensional culture with collagen gel, developed recently for the in vitro study of some mammalian cells in a more physiological condition than a monolayer culture, was applied for a biological study of unilocular fat cells. Successfully embedded in the gel, the unilocular fat cells were shown to be able to keep their cellular function and actively proliferate. These findings confirm that...

During the last decade, virtual goods have become an important target of consumption online (especially in games, virtual worlds and social networking services) amongst physical and digital goods. In this study we investigate the question of why do people purchase virtual goods by conducting a metaanalysis (random effects model) of the existing quantitative body of literature (24 studies) on th...

This paper investigates determinants that influence on consumers’ attitudes toward nondeceptive counterfeit fashion products and behavioral intention to purchase them. The results show that brand image, social influence and previous experiences have a positive impact on consumers’ attitudes toward counterfeit fashion products. Meanwhile, personal gratification has a negative effect on counterfe...

The clonogenic (or colony forming) assay has been established for more than 50 years; the original paper describing the technique was published in 1956. Apart from documenting the method, the initial landmark study generated the first radiation-dose response curve for X-ray irradiated mammalian (HeLa) cells in culture. Basically, the clonogenic assay enables an assessment of the differences in ...

BACKGROUND Multiple cellular functions are compromised in amyotrophic lateral sclerosis (ALS). In familial ALS (FALS) with Cu/Zn superoxide dismutase (SOD1) mutations, the mechanisms by which the mutation in SOD1 leads to such a wide range of abnormalities remains elusive. METHODOLOGY/PRINCIPAL FINDINGS To investigate underlying cellular conditions caused by the SOD1 mutation, we explored mut...