نتایج جستجو برای: adf
تعداد نتایج: 2787 فیلتر نتایج به سال:
PURPOSE Adult T cell leukemia derived factor (ADF) is a human homologue of thioredoxin (hTx), which exhibits scavenging activity with reactive oxygen intermediates. In their previous study, the authors found that after transient retinal ischemia, the expression of thioredoxin in rat retinal pigment epithelium (RPE) layer increased markedly. The present investigation is to determine intracellula...
Spider dragline silk, which exhibits extraordinary strength and toughness, is primarily composed of two related proteins that largely consist of repetitive sequences. In most spiders, the repetitive region of one of these proteins is rich in prolines, which are not present in the repetitive region of the other. The absence of prolines in one component was previously speculated to be essential f...
Proteins of the actin-depolymerizing factor (ADF)/cofilin family have been shown to be crucial for the motility and survival of apicomplexan parasites. However, the mechanisms by which ADF proteins fulfill their function remain poorly understood. In this study, we investigate the comparative activities of ADF proteins from Toxoplasma gondii and Plasmodium falciparum, the human malaria parasite,...
The effect of Arabidopsis thaliana ADF1 and human ADF on the number of filaments in F-actin solutions has been examined using a seeded polymerization assay. ADF did not sever filaments in a catalytic fashion, but decreased the steady-state length distribution of actin filaments in correlation with its effect on actin dynamics. The increase in filament number was modest as compared with the larg...
An adaptive enhancement method is proposed to improve recognition accuracy on the outputs of blind speech separation (BSS) system based on adaptive decorrelation filtering (ADF) in diffuse noise. A divide and conquer strategy is taken to deal with the noise effects on both system adaptation and ADF outputs. First, fast noise compensation (NC) is performed for filter adaptation, forcing ADF to f...
This study investigated the effects of using Socratic questioning to enhance students’ critical thinking (CT) skills in asynchronous discussion forums (ADF) in university-level distance learning courses. The research effort empirically examined two coherent subjects: (a) the efficacy of teaching and modeling Socratic questioning for developing students’ CT skills in ADF and (b) the persistence ...
Identifying explosive bubbles under the influence of their periodically collapsing property has long been a concern in bubble testing literature. In this paper, we argue that the sup Augmented Dickey-Fuller (ADF) test (Phillips, Wu and Yu, 2009), which implements a right-tail ADF test and a sup test on a forward expanding sample sequence, is sensitive to the sample starting point when there are...
Many concurrent programs require some form of conditional synchronization to coordinate the execution of different program tasks. Programming these algorithms using transactional memory (TM) often results in a high conflict rate between transactions. In this paper we propose an Atomic dataflow model ADF, which aims to reduce transaction conflicts by incorporating dataflow scheduling principles ...
Cofilin and its closely related protein, actin-depolymerizing factor (ADF), are key regulators of actin cytoskeleton dynamics that have been implicated in growth cone motility and neurite extension. Cofilin/ADF are inactivated by LIM kinase (LIMK)-catalyzed phosphorylation and reactivated by Slingshot (SSH)-catalyzed dephosphorylation. Here we examined the roles of cofilin/ADF, LIMKs (LIMK1 and...
Hair cells, the inner ear's sensory cells, are characterized by tens to hundreds of actin-rich stereocilia that form the hair bundle apparatus necessary for mechanoelectrical transduction. Both the number and length of actin filaments are precisely regulated in stereocilia. Proper cochlear and vestibular function also depends on actin filaments in nonsensory supporting cells. The formation of a...
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