34 children aged 9 months to 12 years presenting with chronic and intermittent rectal bleeding were diagnosed as having colorectal polyps by fiberoptic colonoscopy performed under sedation. bleeding per rectum (mean duration, 15 months) was the chief presenting symptom and was present in 97% of these patients. in 85% of patients polypectomy was carried out without using general anesthesia. 7r% ...

Colon cancer is the third most common type of cancer in the United States of America. Every year about 140,000 people are newly diagnosed with colon cancer. Early detection is crucial for a successful therapy. The standard screening procedure is called colonoscopy. Using this endoscopic examination physicians can find colon polyps and remove them if necessary. Adenomatous colon polyps are deeme...

Monoclonal antibodies raised by synthetic peptide immunisation were used to determine the distribution of the protein product of the c-myc gene by immunocytochemical staining of archival wax embedded material from patients with familial adenomatous polyposis. Polyps from 18 cases of familial adenomatous polyposis, 10 of whom had developed malignant change, and 30 normal control colonic biopsy s...

aim :  the aim of this study was to present the demographic and clinical characteristics of patients with gastric polypoid lesions and to study the histopathologic features of these lesions. background : the frequency of gastric polyps is gradually increasing due to the widespread use of endoscopic examinations. patients and methods : clinical and endoscopic features of 100 gastric polyposis pa...

The penetrance for colon polyps is close to 100% and bi-allelic MUTYH mutation carriers generally develop 10-100’s adenomatous polyps/adenomas of the colon and the rectum. Approximately one third of patients also develop polyps/adenomas in the upper gastrointestinal tract. Other manifestations frequently seen in Familial Adenomatous Polyposis (FAP) are also present in minority of MAP patients: ...

BACKGROUND occasionally, the risk of malignant transformation may be difficult to establish in adenomatous polyps due to the fact that they contain areas with variable grades of dysplasia. A measurement of tissue tumor markers may be useful to recognize these adenomas. OBJECTIVES the aims of this study were: to established firstly the relationship between carbohydrate antigen 19.9 (CA-19.9) c...

Ras gene family (c-Ha, Ki, N ras) and c-myc proto-oncogenes were analyzed in seven colonic and three gastric adenomatous polyps obtained from a patient with Turcot's syndrome. The rearrangement and amplification as well as overexpression of c-Ha ras gene in one colonic adenomatous polyp were determined. The amplified c-Ha ras gene in this polyp revealed larger fragments of BamHI, PstI and SacI ...

INTRODUCTION Serrated polyposis syndrome (SPS) is a rare entity characterized by the presence of multiple hyperplastic polyps in the colon and an increased risk of presentation and development of colorectal cancer (CRC). OBJECTIVE To evaluate the clinical and phenotypical characteristics of patients that present one of the 3 WHO criteria for the diagnosis of SPS diagnosed and treated a tour h...

Epidemiological and animal studies suggest a role for calcium in the chemoprevention of colorectal neoplasia. This study was designed to investigate whether supplemental oral calcium has a suppressant effect on colonic mucosal ornithine decarboxylase (ODC) and tyrosine kinase activities in patients with adenomatous polyps or a history of adenomatous polyps and whether this is affected by age. O...