نتایج جستجو برای: adeabc

تعداد نتایج: 71  

Journal: :The Journal of antimicrobial chemotherapy 2014
Qiong Chen Xi Li Hua Zhou Yan Jiang Yan Chen Xiaoting Hua Yunsong Yu

OBJECTIVES Acinetobacter baumannii is an important opportunistic pathogen and multidrug-resistant isolate. Although tigecycline is a potent antibiotic for treating infections with multidrug-resistant isolates, resistance is becoming a problem. This study aimed to explore the mechanism of tigecycline resistance in A. baumannii. METHODS A serial passage experiment was performed to collect isola...

2010
Sébastien Coyne Patrice Courvalin

24 Among Acinetobacter spp., A. baumannii is the most frequently implicated in nosocomial 25 infections, in particular in intensive care units. It was initially thought that multidrug 26 resistance (MDR) in this species was mainly due to horizontal acquisition of resistance genes. 27 However, it has become recently obvious that increased expression of chromosomal genes for 28 efflux systems pla...

2013
Lingxiang Zhu Zhongqiang Yan Zhaojun Zhang Qiming Zhou Jinchun Zhou Edward K. Wakeland Xiangdong Fang Zhenyu Xuan Dingxia Shen Quan-Zhen Li

BACKGROUND The emergence and rapid spreading of multidrug-resistant Acinetobacter baumannii strains has become a major health threat worldwide. To better understand the genetic recombination related with the acquisition of drug-resistant elements during bacterial infection, we performed complete genome analysis on three newly isolated multidrug-resistant A. baumannii strains from Beijing using ...

الوندی, امیرهوشنگ , دوستوندی, سوزان, عبیری , رامین, مهاجری, پرویز ,

Background and purpose: Acinetobacter spp. is a non-fermentative gram- negative bacterium involving in various nosocomial infections. During last decade increasing number of multidrug-resistant isolates of Acinetobacter spp. have been reported. This type of resistance is possibly related to efflux pumps. This research aimed at identifying the phonotypic and genotypic characteristics of efflux p...

Journal: :infection, epidemiology and medicine 0
goli angoti department of microbiology, shahid beheshti university, m.c international branch, tehran, ir iran mojgan bandehpour department of biotechnology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran hossein goudarzi shahid beheshti university. m.c. international branch, tehran, ir iran maryam hajizadeh department of microbiology, imam reza hospital, tabriz, ir iran maryam zarringhalam moghaddam department of microbiology, shahid beheshti university, m.c international branch, tehran, ir iran amaneh kouchaki department of biotechnology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran

background: the importance of this research was to determine the prevalence of efflux pump genes among acinetobacter baumannii isolates from hospitalized patients in imam reza hospital in tabriz, iran. materials and methods: this descriptive study was conducted in the imam reza hospital, tabriz, ir iran during june 2013 to march 2014. twenty-six strains were isolated from female patients (42.6%...

2016
Karl A Hassan Amy K Cain TaoTao Huang Qi Liu Liam D H Elbourne Christine J Boinett Anthony J Brzoska Liping Li Martin Ostrowski Nguyen Thi Khanh Nhu Tran Do Hoang Nhu Stephen Baker Julian Parkhill Ian T Paulsen

UNLABELLED Multidrug efflux pumps provide clinically significant levels of drug resistance in a number of Gram-negative hospital-acquired pathogens. These pathogens frequently carry dozens of genes encoding putative multidrug efflux pumps. However, it can be difficult to determine how many of these pumps actually mediate antimicrobial efflux, and it can be even more challenging to identify the ...

ژورنال: :مجله دانشگاه علوم پزشکی مازندران 0
سوزان دوستوندی susan dostvandi msc in microbiology, department of microbiology, faculty of basic sciences, islamic azad university, sanandaj branch, sanandaj, iranکارشناسی ارشد میکروبیولوژی، دانشکده علوم پایه، دانشگاه آزاد اسلامی واحد سنندج، سنندج، ایران رامین عبیری ramin abiri assistanr of professor, department of microbiology, faculty of medicine, kermanshah university of medical sciencesاستادیار، گروه میکروب شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران پرویز مهاجری parviz mohajeri assistanr of professor, department of microbiology, faculty of medicine, kermanshah university of medical sciencesاستادیار، گروه میکروب شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران امیرهوشنگ الوندی amirhooshang alvandi assistanr of professor, department of microbiology, faculty of medicine, kermanshah university of medical sciencesکرمانشاه: بلوار شهید شیرودی، خیابان پرستار، دانشکده پزشکی، گروه میکروب شناسی

چکیده سابقه و هدف: سویه های اسینتوباکتر با مقاومت چندگانه در دهه اخیر شایع شده است که ممکن است در نتیجه فعالیت پمپ های ایفلاکس باشد. مطالعه حاضر به منظور بررسی فنوتیپ و ژنوتیپ پمپ های ایفلاکس در ایزوله های گونه های اسینتوباکتر جدا شده از بیماران بستری در بیمارستان های امام رضا و طالقانی کرمانشاه در سال 1392 انجام شده است. مواد و روش ها: در یک مطالعه توصیفی-تحلیلی 100 ایزوله گونه های اسینتوباکتر...

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