OBJECTIVE To review the characteristic features of patients with advanced liver disease that may lead to increased perioperative morbidity and mortality rates. DESIGN Literature review. RESULTS Patients with end-stage liver disease are at high risk of major complications and death following surgery. The most common complications are secondary to acute liver failure and include severe coagul...

Gunn rats, a mutant strain of rats, suffer from autosomal recessive hyperbilirubinemia. The homozygotes (j/j) develop jaundice soon after birth and often exhibit kernicterus and cerebellar hypoplasia that are due to bilirubin. Therefore, j/j Gunn rats have been used as an animal model of bilirubin encephalopathy, as well as of neonatal hyperbilirubinemia. In this review, we discuss morphologica...

In July 2004, the Subcommittee on Hyperbilirubinemia of the American Academy of Pediatrics (AAP) published its clinical practice guideline on the management of hyperbilirubinemia in the newborn infant 35 weeks of gestation,1 and a similar guideline was published in 2007 by the Canadian Paediatric Society.2 Experience with implementation of the AAP guideline suggests that some areas require clar...

INTRODUCTION Experience with lamivudine treatment for acute severe hepatitis B is limited. Fulminant hepatitis develops in 1% of immunocompetent patients with acute hepatitis B. OBJECTIVE The aim of this study was to evaluate the efficacy of lamivudine in the treatment of severe acute hepatitis B (SAHB) in immunocompetent adult patients. METHODS Between January 2006 and May 2013 at the Clin...

Neonatal jaundice is a common physiological problem affecting over half of all full term and most preterm infants. Thus, newborn infants must be monitored for signs of hyperbilirubinemia to prevent acute bilirubin encephalopathy or kernicterus. Evidence exists supporting the benefits of baby massage as a form of mild hand to skin contact, to increase neonatal physical and mental development. In...

risk factors for Fulminant Hepatic Failure (FHF) in (37.50%), and grade 2 in 25 (31.25%). Forty five children at a tertiary care hospital, Sukkur. (56.25%) patients expired. Patients with bilirubin Methodology: Retrospective review of patients 13.0±8.0 mg/dl vs 6.7±3.3 mg/dl recovered. ALT 1-14years, admitted with FHF from July 2007 to was lower in expired patients 467±381 IU/L vs June 2012, at...

Background: Acute kidney injury remains a common complication with poor prognosis, and is significant predictor of mortality in cirrhosis patients. We aimed to determine the percentage acute decompensated patients evaluate treatment results as well several factors related Methods: A prospective study was conducted on Can Tho City, Vietnam, from 2019 2020. Decompensated were found have admission...