Conversion of a ‘rough’ typical strain of Actinomyces israelii of human origin to a ‘smooth’ soft form more tolerant of oxygen was found to result from the physical trapping within the mycelium of a few alien and facultatively anaerobic cells. Such cells, which commonly proved to be staphylococci, were isolated in single cell culture by micromanipulative techniques and then grown aerobically. T...

Pediatric cervicofacial actinomycosis is a rare occurrence consequent to dental infections and manipulations or maxillofacial trauma. The clinical presentation ranges from multiple draining sinuses to swellings resembling tumors and cysts. The present unusual case had congenital dermoid cyst of mid upper lip with Actinomyces israelii infection identified on microscopy, culture, and histopatholo...

Actinomyces israelii is a branching anaerobic bacilli microorganism that can be identified as normal flora throughout various portions of the human alimentary canal. It is crucial to establish a diagnosis as treatment will vary depending on the clinical form of the disease. We report a case of a 78-year-old man who initially presented with an acute onset of respiratory distress displayed contra...

OBJECTIVE This study was conducted to assess the susceptibility of human clinical isolates of Actinomyces species to 12 antimicrobial agents. METHODS Human clinical isolates of Actinomyces spp. were collected from stored collections held at the Microbiology Department, Edinburgh University, Anaerobe Reference Laboratory, Cardiff, Glasgow Dental Hospital and Glasgow Royal Infirmary. Each isola...

discharge, multiple nodules, and deformity of his right hand (Figure 1). His symptoms had begun with pain and swelling without trauma 16 years ago. He had been diagnosed with chronic actinomyces osteomyelitis and underwent medical therapy and surgical debridement in four different incidents. He had been on antibiotics irregularly for 12 years. Deformity was evident, there was no active wrist mo...

introduction: one of the main goals of endodontic treatment is to decrease the harboring bacteria within the root canal system and dentinal tubules. this experimental study attempted to investigate the antibacterial efficacy of three root canal irrigants in the presence and absence of smear layer (sl). methods and materials: a total of 210 sound extracted human single-rooted teeth were prepared...

Actinomycosis is a rare disorder caused by an anaerobic gram-positive bacillus (Actinomyces), predominantly by the Actinomyces israelii species. Only 20% of cases show an abdominal manifestation, the appendix and ileocecal valve being the most frequent locations. Definitive diagnosis is based on microbiological cultures, microscopy or macroscopy examination. Nevertheless, histological examinati...

The effect of dextranases (EC 3.2.1.11) from the oral isolates Actinomyces israelii and Bacteroides ochraceus on water-insoluble glucan production by the Streptococcus mutans dextransucrase (EC 2.4.1.5) and sucrose-dependent adherence to smooth glass surfaces by S. mutans was studied. Collection on membrane filters of water-insoluble polysaccharides synthesized from radioactive sucrose was used...

Menaquinones were the only isoprenoid quinones found in 48 corynebacteria and actinomycete strains examined. Dihydromenaquinones having nine isoprene units were the main components isolated from Gordona, Mycobacterium, Corynebacterium bovis, Corynebacterium glutamicum and a strain labelled Nocardia farcinica, but dihydromenaquinones having eight isoprene units were characteristic of other Coryn...