Epidermolysis bullosa pruriginosa, a genetic mechanobullous disease, is characterized by pruritus, lichenified or nodular prurigo-like lesions, occasional trauma-induced blistering, excoriations, milia, nail dystrophy and albopapuloid lesions, appearing at birth or later. Scarring and prurigo are most prominent on the shins. Treatment is unsatisfactory. We report three such cases: two of them f...

Prurigo nodularis (PN) is a subtype of chronic prurigo presenting single to multiple symmetrically distributed, hyperkeratotic and intensively itching papules and nodules. PN evolves along with chronic pruritus in the context of diverse dermatological, systemic, neurological or psychiatric conditions. Permanent scratching is possibly a major trigger of PN, although its exact pathophysiology rem...

Background: Recent findings establish the 308 xenon chloride (XeCl) excimer laser (EL) to be a new option in the area of UVB phototherapy. Since the EL enables high radiant exposure of narrow-band (NB) UVB and precise targeting of affected skin, it appears to be a promising treatment for the prurigo form of atopic dermatitis (AD). Objectives: To investigate the efficacy and safety of the excime...

The introduction of topical calcineurin inhibitors resulted in a significant improvement in the treatment of atopic dermatitis. In addition, rapid amelioration of pruritus could be observed. In case reports, other pruritic dermatoses such as chronic irritative hand dermatitis, rosacea, graft-versus-host-disease, and lichen sclerosus were also treated successfully with pimecrolimus and tacrolimu...

CARP: confluent and reticulated papillomatosis PP: prurigo pigmentosa INTRODUCTION Prurigo pigmentosa (PP) is an uncommon, acquired inflammatory disorder with a predilection for young adults of Asian descent. This condition is manifested by highly pruritic, reticulated, and erythematous papules that resolve with hyperpigmentation. Multiple cases of PP have been reported since its initial descri...

It is widely accepted that elastotic changes of the skin are primarily an indicator of cumulative sun exposure of the dermis and are a characteristic finding of actinic keratoses. To date, there have been few reports that measure the amount of elastic tissue objectively and quantitatively, especially in actinic keratoses. The computerized image analysis method has proved useful recently in dete...

Prurigo pigmentosa is a type of inflammatory dermatosis characterized by symmetrical pruritic erythematous papules that normally resolve with reticular pigmentation. In severe cases, edematous infi ltrative plaques may be found, but usually no vesicles or bullae. We presented a 32-year-old Taiwanese female, a case of insulin dependent diabetis mellitus with sudden onset of vesicobullae upon ery...

on his lower back and upper extremities. Each eruption was a bean-sized solitary papule ( fig. 1 a). Many of the papules had erosions or crusts due to excoriation. Some papules were arranged linearly or clustered to form small plaques. Steroid ointment was ineffective. He also had other cutaneous manifestations of dermatomyositis such as heliotrope rash, flagellate erythema of the upper back, p...