Stress fibres form a fully integrated meshwork with the submembranous contractile actin cortex that generates and propagates traction forces across entire cell.

Neuronal damage is a major consequence of bacterial meningitis, but little known about mechanisms interaction with neurons leading to neuronal cell death. Streptococcus pneumoniae (pneumococcus) cause meningitis and many survivors develop neurological sequelae after the acute infection has resolved, possibly due damage. Here, we studied for pneumococcal interactions neurons. Using human primary...

High temperature stress is one of the most threatening abiotic stresses for plants limiting crop productivity world-wide. Altered developmental responses to moderate-high has been shown be linked intracellular auxin homeostasis regulated by both biosynthesis and transport. Trafficking carrier proteins plays a major role in maintaining cellular homeostasis. The trafficking largely relies on cyto...

Actin microfilaments (F-actin) are major components of the cytoskeleton essential for many cellular dynamic processes (vesicle trafficking, cytoplasmic streaming, organelle movements). The aim this study was to examine whether cortical actin might be implicated in regulation nutrient uptake root and leaf cells Beta vulgaris. Using antibodies raised against AtSUC1 sucrose transporter, immunochem...

Most eukaryotic cells rely on localized actin polymerization to generate and sustain the protrusion activity necessary for cell movement [1, 2]. Such protrusions are often in the form of a flat lamellipod with a leading edge composed of a dense network of actin filaments [3, 4]. The Arp2/3 complex localizes within that network in vivo [3, 4] and nucleates actin polymerization and generates a br...

Actin cytoskeletal protrusions in crawling cells, or lamellipodia, exhibit various morphological properties such as two characteristic peaks in the distribution of filament orientation with respect to the leading edge. To understand these properties, using the dendritic nucleation model as a basis for cytoskeletal restructuring, a kinetic-population model with orientational-dependent branching ...