نتایج جستجو برای: acidic zinc bath

تعداد نتایج: 123775  

Journal: :Cell 1989
G Mardon D C Page

The ZFY gene, located in the sex-determining region of the human Y chromosome, appears to encode a zinc-finger protein. Two homologous genes, Zfy-1 and Zfy-2, are found in the sex-determining region of the mouse Y chromosome. One or both genes may serve as the primary sex-determining signal in mice. Both Zfy-1 and Zfy-2 are transcribed in the adult testis. Nucleotide sequence analysis of a Zfy-...

Journal: :FEBS letters 2013
Lise H Montpellier Stefan Siemann

Translocation of the zinc-dependent metalloendopeptidase anthrax lethal factor (LF) from the endosome to the cytosol requires an acidic endosomal milieu. In the current study, we utilized immobilized (to prevent protein aggregation below pH 5.5) and native LF to assess the effect of pH on the function and metal content of LF. Our results reveal the diminution of LF's catalytic competence under ...

2005
S. E. Han H. G. Lee C. H. Yun Z. S. Hong S. H. Kim S. K. Kang J. S. Cho

Zinc is a trace element that is associated with a stimulation of immune function and regulation of ion balance for livestock production. In this study, the effect of zinc as inhibitor to apoptosis-induced cells was examined in vitro using mammary epithelial cell line, HC11 and macrophage cell line, NCTC3749. Cell viability, measured by MTT assay, indicated that 10 g/ml of zinc had a negative im...

Journal: :Journal of the Mining and Metallurgical Institute of Japan 1973

Journal: :International journal of physiology, pathophysiology and pharmacology 2012
Qian Jiang Xiang-Ming Zha Xiang-Ping Chu

Acid-sensing ion channel 1b (ASIC1b) is expressed in peripheral sensory neurons and has been implicated in nociception. Understanding the modulation of ASIC1b will provide important insight into how ASIC1b contributes to pain sensation. In our previous study, we showed that zinc, an important modulator of pain sensation, reduces rat ASIC1b current. However, rat ASIC1b shows several important di...

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