N,N'-((dodecane-1,12-diylbis(azanediyl))bis(carbonothioyl))bis(4-nitrobenzamide) 5 and N,N'-((dodecane-1,12-diylbis(azanediyl))bis(carbonothioyl))bis(3-nitrobenzamide) 6 as bis acyl thiourea derivatives were synthesized their molecular structures characterized using 1H NMR, 13C COSY, DEPT, HMQC, FT-IR, HRMS techniques. The acid dissociation constants (pKa) of the bis-acyl 5, determined potentio...

In connection with attempts in this laboratory to increase the yields of threonine in isolations from various prtiteins, it recently became essential to determine its isoelectric point. During the time since the isolation and identification of threonine by Rose and coworkers (1) and its subsequent synthesis by West and Carter (2), the isoelectric point of the pure compound has not been reported...

We report the kinetics of the reactions of unconjugated bilirubin and conjugated bilirubin with p-diazobenzene sulfonic acid in aqueous media. Our studies confirm that each reaction proceeds in two steps and that the second step is catalyzed by sulfanilic acid. In the presence of an excess of p-diazobenzenesulfonic acid and in the absence of sulfanilic acid, the reaction for either unconjugated...

A spectrophotometric method was used to determine the acidity constant of 4'-carboxybenzo-24-crown-8 in 52% (w/w) ethanol-water mixture. The acid dissociation constant, Ka, was found to increase in the presence of Na+, K+, Rb+, Cs+ and Tl+ ions. The formation constants of the resulting 1:1 complexes between the carboxycrown a...