Absence seizures are generalized, cortico-thalamo-cortical (CTC) high power electroencephalographic (EEG) or electrocorticographic (ECoG) events that initiate and terminate suddenly. ECoG recordings of absence seizures in animal models of genetic absence epilepsy show a sudden spike-wave-discharge (SWD) onset that rapidly emerges from normal ECoG activity. However, given that absence seizures o...

Absence seizures are 5–10 s episodes of impaired consciousness accompanied by 3– 4 Hz generalized spike-and-wave discharge on electroencephalography (EEG). The time course of functional magnetic resonance imaging (fMRI) changes in absence seizures in relation to EEG and behavior is not known. We acquired simultaneous EEG–fMRI in 88 typical childhood absence seizures from nine pediatric patients...

We analyzed surgical results of anterior callosotomy (AC) in 27 patients with intractable symptomatic generalized epilepsy or frontal lobe epilepsy. Excellent outcome (decrease in seizure frequency of greater than 80% or no seizure) was obtained in 59.3%, and 14.8% showed good outcome(decrease in seizure frequency of greater than 50%). There was no significant difference of the results between ...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 91 tion or video review because the diagnosis requires other information, such as age of onset, etiology, family history, seizure frequency, imaging studies, precipitating factors, electroencephalography (EEG) and natural history. Most types of epilepsy are characterized by more than one type of seizure. Patients with focal (or partial) epilepsy may ha...

Changes in seizure type of severe myoclonic epilepsy (SME) in infancy were reviewed retrospectively in 14 patients (11 males and 3 females) who were followed-up to the age of 7 years or more. The observation period ranged from 5 to 16 years with a mean of 10 years. During the follow-up, three or four types of seizures were seen per patient, but the pattern of appearance and disappearance of eac...