OBJECTIVE Impaired glucose metabolism is common in acromegaly, but it is not clear how glucose metabolism is impaired or what predicts its restoration after cure of the disease. To identify factors involved in the impairment of glucose metabolism in acromegaly, we evaluated clinical parameters before and immediately after surgical cure of the disease. DESIGN AND METHODS We retrospectively ana...

Second-generation (atypical) antipsychotic medications are of great benefit to a wide variety of people with psychiatric disorders, especially patients with schizophrenia. However, one constellation of adverse effects is an increased risk of obesity, diabetes, and metabolic syndrome. Increasing numbers of reports concerning impaired glucose tolerance, diabetes, and ketoacidosis have raised conc...

To assess mechanisms for postprandial hyperglycemia, we used a triple-isotope technique ([\3-(3)H]glucose and [(14)C]bicarbonate and oral [6,6-dideutero]glucose iv) and indirect calorimetry to compare components of glucose release and pathways for glucose disposal in 26 subjects with type 2 diabetes and 15 age-, weight-, and sex-matched normal volunteers after a standard meal. The results were ...

The Assessment of Insulin, Glucose and Lipids in Ischemic Thrombotic Cerebrovascular Disease • Sixty-one male patients with ischemic thrombotic cerebrovascular disease (ITCVD) and 61 age-matched controls were studied to determine the interrelationships between the primary risk factors of ITCVD. Impaired carbohydrate metabolism in ITCVD was reflected in the significantly greater number of abnorm...

AIMS The cumulative effect of gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDP) on postpartum cardio-metabolic diseases is equivocal. We aimed to assess the associations of GDM and HDP's individual and synergic contribution to risks of postpartum cardio-metabolic diseases (metabolic syndrome (MetS), abnormal glucose metabolism and hypertension (HTN)). METHODS O...

BACKGROUND About a third of patients with acute stroke and no prior diagnosis of diabetes have hyperglycaemia during the acute phase of stroke. Whether this is an acute stress response or a reflection of underlying diabetes is controversial. AIM To assess whether impaired glucose metabolism in patients with acute ischaemic stroke and no previous diagnosis of diabetes persists after 3 months, ...

Background: Upon check-in, tests were conducted to assess FBG, PPBG, and HbA1c levels in 100 patients. A majority of them, more than half, showed glucose processing issues, with FBG exceeding 100mg/dL. Additionally, 44 patients had increased values. follow-up after two weeks revealed that roughly 64% still impaired metabolism. Encouragingly, this number dropped just 42% a month. concerning obse...