نتایج جستجو برای: abcd2

تعداد نتایج: 187  

Journal: :Biochemical and Biophysical Research Communications 2015

Journal: :Stroke 2014
Elaine T Miller Debbie Summers

C onsidered a medical emergency, a transient ischemic attack (TIA) resulting from a focal ischemia in the brain or retina signals a sudden neurological deficit with patient symptoms typically lasting only 1 to 2 hours. The 90-day risk of stroke after a TIA is reported as high as 17% with the highest risk occurring in the first week. Approximately 240 000 US adults each year experience a TIA. 5 ...

Journal: :Arquivos de neuro-psiquiatria 2013
Norberto L Cabral Adriana B Conforto

The 2012 Brazilian guidelines for ischemic stroke recommended periodic educational programs to increase stroke awareness among medical professionals, other health professionals, and emergency services1. Also, a Brazilian National Stroke Policy Act published in 2012 established the battle against stroke as a national priority. Education about stroke is a crucial element of this policy. Recogniti...

Journal: :Stroke 2011
Jean-Marc Olivot Connie Wolford James Castle Michael Mlynash Neil E Schwartz Maarten G Lansberg Stephanie Kemp Gregory W Albers

BACKGROUND AND PURPOSE To evaluate a novel emergency department-based TIA triage system. METHODS We developed an approach to TIA triage and management based on risk assessment using the ABCD(2) score in combination with early cervical and intracranial vessel imaging. It was anticipated that this triage system would avoid hospitalization for the majority of TIA patients and result in a low rat...

Journal: :Human molecular genetics 2010
Stéphane Fourcade Montserrat Ruiz Cristina Guilera Eric Hahnen Lars Brichta Alba Naudi Manuel Portero-Otín Georges Dacremont Nathalie Cartier Ronald Wanders Stephan Kemp Jean Louis Mandel Brunhilde Wirth Reinald Pamplona Patrick Aubourg Aurora Pujol

X-linked adrenoleukodystrophy (X-ALD) is a fatal, axonal demyelinating, neurometabolic disease. It results from the functional loss of a member of the peroxisomal ATP-binding cassette transporter subfamily D (ABCD1), which is involved in the metabolism of very long-chain fatty acids (VLCFA). Oxidative damage of proteins caused by excess of the hexacosanoic acid, the most prevalent VLCFA accumul...

2014
Alina Beliavsky Jeffrey J. Perry Dar Dowlatshahi Jason Wasserman Marco L.A. Sivilotti Jane Sutherland Andrew Worster Marcel Émond Grant Stotts Albert Y. Jin Wieslaw J. Oczkowski Demetrios J. Sahlas Heather E. Murray Ariane MacKey Steve Verreault George A. Wells Ian G. Stiell Mukul Sharma

BACKGROUND Isolated dysarthria is an uncommon presentation of transient ischemic attack (TIA)/minor stroke and has a broad differential diagnosis. There is little information in the literature about how often this presentation is confirmed to be a TIA/stroke, and therefore there is debate about the risk of subsequent vascular events. Given the uncertain prognosis, it is unclear how to best mana...

Journal: :Cerebrovascular diseases 2013
Anastasios Chatzikonstantinou Marc E Wolf Anke Schaefer Michael G Hennerici

BACKGROUND Prognostic clinical scores (ABCD2 and ABCD3-I), as well as specific clinical signs and symptoms (e.g. fluctuations) have been used to predict early stroke risk in patients admitted to hospital after transient ischemic attacks (TIAs). We compared the utility of these scores and signs for prognosis and outcome. METHODS 235 patients with TIAs admitted to our Comprehensive Stroke Cente...

Journal: :The British journal of general practice : the journal of the Royal College of General Practitioners 2013
Daniel Lasserson

Not only do we advise our patients and offer interventions to control vascular risk factors but we are often the first port of call for patients seeking health care after a transient ischaemic attack (TIA). 1 The neurologist's definition of TIA has recently changed and patients must have had a transient clinical deficit suggesting focal brain or retinal dysfunction with a 'tissue' criterion of ...

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