Patients with sickle cell anemia (SCA) are at increased risk for developing chronic kidney disease (CKD), and progression to end-stage renal is associated morbidity mortality. Identifying modifiable factors CKD in childhood a vital first step ameliorate progression. SCA may have higher due the unique pathophysiology heme exposure sickling of red blood cells; however, it important evaluate estab...

introduction: the process of urbanism in countries that are developing, like islamic republic of iran with increasing of the number and the size of cities and the fast accepting of population have been caused the forming of problems like an in-official economics and in-official settlement and was become creating high population in main and old places of city and increasing of air pollution and ...

•Myasthenia gravis patients have a significant disease burden in addition to muscle weakness.•Fatigue is prominent subgroup of with myasthenia gravis.•Patient-reported data illustrate limitations daily activities and quality life gravis.•Comorbidities treatment side-effects should be evaluated all gravis.•Optimal specialized care for local, national global perspective. Patients chronic often wo...