Hydrogen absorption performances of LaNi5 alloy are sensitive to the surface reactions with poisonous gases, such as oxygen, readily forming oxides/hydroxides. In this study, we report studies on hydrogen behaviour AB5-type storage alloys, formed by LaNi(5–x)Snx (X = 0.2) followed electroless Pd deposition. The uncoated and Pd-coated materials were characterized using scanning electron microsco...

Subtilase cytotoxin (SubAB) is a recently identified AB5 subunit toxin produced by Shiga-toxigenic Escherichia coli. The A subunit is thought to be a subtilase-like, serine protease, whereas the B subunit binds to the toxin receptor on the cell surface. We cloned the genes from a clinical isolate; the toxin was produced as His-tagged proteins. SubAB induced vacuolation at concentrations greater...

Shiga toxin (Stx) is an AB5 ribotoxin made by Stx-producing Escherichia coli (STEC). These organisms cause diarrhea, hemorrhagic colitis and the hemolytic uremic syndrome. STEC make two types of Stxs, Stx1 and/or Stx2. Stx2 has one prototype (a) and six subtypes (b-g), but only STEC that make Stx2a, and/or Stx2c, or Stx2d are associated with severe disease. However, Stx2c is about 10-fold less ...

The five B-subunits (CTB5) of the Vibrio cholerae (cholera) toxin can bind to the intestinal cell surface so the entire AB5 toxin can enter the cell. Simultaneous binding can occur on more than one of the monosialotetrahexosylganglioside (GM1) units present on the cell surface. Such simultaneous binding arising from the toxins multivalency is believed to enhance its affinity. Thus, blocking the...

Subtilase cytotoxin (SubAB) is the prototype of a recently emerged family of AB5 cytotoxins produced by Shiga-toxigenic Escherichia coli (STEC). Its mechanism of action involves highly specific A-subunit-mediated proteolytic cleavage of the essential endoplasmic reticulum (ER) chaperone BiP. Our previous in vivo studies showed that intraperitoneal injection of purified SubAB causes a major redi...

This work presents a model to determine productivity and heat consumption of hydrogen compression utilising metal hydrides (MH) by using Pressure – Composition Temperature (PCT) diagrams the MH materials at defined operating conditions temperatures pressures. The present Part I is focused on analysis performances several AB5- AB2-type intermetallic alloys which, when between 20 150 °C, provide ...