Hypoallergenic formulas containing hydrolyzed protein are intended for use by infants to prevent cow’s milk allergy. The degree of hydrolysis epitopic areas determines the residual allergenicity whey hydrolysates (WPHs). However, only amino-acid-based infant (IFs) considered entirely nonallergenic. aim this study was investigate four commercially available WPHs with different (H1–H4) potential ...

Electrically controllable deoxyribonuclic acid (DNA) nanolevers are used to investigate the binding interaction between Influenza A/Aichi/2/1968 and peptide called “PeB”, which specifically binds viral surface protein hemagglutinin. PeB is immobilized on gold electrodes of a “switchSENSE” biochip by conjugation DNA-strands that hybridized complementary anchors. The surface-tethered DNA strand c...

Abstract T cell immunity to viruses and cancers is crucially dependent on the surface display of major histocompatibility complex class I (MHC-I) molecules selectively loaded with high affinity peptides. Peptide loading occurs in ER within a multimolecular assembly known as peptide (PLC). A critical component PLC tapasin, 45 kDa membrane glycoprotein whose absence expression stability MHC-I are...

Recently, antimicrobial peptides have been introduced as potent antibiotics with a wide rangeof antimicrobial activities. They have also exhibited other biological activities, including antiinflammatory,growth stimulating, and anti-cancer activities. In this study, an analog of MagaininII was designed and produced as a recombinant fusion protein. The designed sequence containe...

Ultrasmall gold nanoparticles with a metallic core diameter of 2 nm were surface-conjugated peptides that selectively target epitopes on the surface WW domain model protein hPin1 (hPin1-WW). The binding to was accomplished via thiol group terminal cysteine. particles analyzed by NMR spectroscopy, high-resolution transmission electron microscopy, and differential centrifugal sedimentation. loadi...