objective: punica granatum, commonly known as pomegranate, has emerged as a medicinal plant with potential antimicrobial activity. the present study was planned to evaluate this activity against both gram positive staphylococcus aureus (s. aureus) and negative pseudomonas aeruginosa (p. aeruginosa) bacteria as well as against pathogenic yeast, candida albicans (c. albicans). material and method...

objectives: biomechanical preparation and irrigation with antimicrobial solutions are necessary to disinfect the root canal space. this in vitro study aimed to examine the antifungal effect of green tea extract on candida albicans biofilm formed on tooth substrate. materials and methods: minimum fungicidal concentration (mfc) and minimum inhibitory concentration at which 90% of the isolates wer...

Candida dubliniensis is an emerging pathogenic yeast species closely related to Candida albicans and frequently found colonizing or infecting the oral cavities of HIV/AIDS patients. Drug resistance during C. dubliniensis infection is common and constitutes a significant therapeutic challenge. The calcineurin inhibitor FK506 exhibits synergistic fungicidal activity with azoles or echinocandins i...

Iron availability is a central factor in infections, since iron is a critical micronutrient for all living organisms. The host employs both iron limitation and toxicity strategies to control microbial growth, and successful pathogens are able to tightly coordinate iron homeostasis in response to changing iron levels. As a commensal and opportunistic pathogen, Candida albicans copes with both ir...

background: in recent years, drug resistance to human pathogenic fungi has been increased. medicinal plants are one way to overcome antibiotic resistance. the aim of this study was to evaluate the antifungal and inhibitory activity of five medicinal plants on the growth of candida albicans. methods: this study was done in the microbiology lab of shahid bahonar university of kerman, iran in 2015...

Objective: Punica granatum, commonly known as pomegranate, has emerged as a medicinal plant with potential antimicrobial activity. The present study was planned to evaluate this activity against both Gram positive Staphylococcus aureus (S. aureus) and negative Pseudomonas aeruginosa (P. aeruginosa) bacteria as well as against pathogenic yeast, Candida albicans (C. albicans). Material and Metho...

Candida albicans is an opportunistic human fungal pathogen that causes candidiasis. As healthcare has been improved worldwide, the number of immunocompromised patients has been increased to a greater extent and they are highly susceptible to various pathogenic microbes and C. albicans has been prominent among the fungal pathogens. The complete genome sequence of this pathogen is now available a...

The urgent need to treat multi-drug resistant pathogenic microorganisms in chronically infected patients has given rise to the development of new antimicrobials from natural resources. We have tested Elaeis guineensis Jacq (Arecaceae) methanol extract against a variety of bacterial, fungal and yeast strains associated with infections. Our studies have demonstrated that E. guineensis exhibits ex...

BACKGROUND Natural killer (NK) cells are innate lymphocytes with potent cytotoxic activity. Whereas activity of NK cells has been demonstrated against the fungal pathogens Aspergillus fumigatus and Cryptococcus neoformans, little was known about their interaction with Candida albicans. METHODS Primary human NK cells were isolated from buffy coats, primed with a cytokine cocktail and used for ...

long-term use of orthodontic appliances and fixation ligatures creates a favorable environment for the accumulation of oral normal microflora and increases the risk of enamel demineralization and periodontal disease. the aim of this study was to compare the antimicrobial effects of zataria multiflora extract and 0.2% chlorhexidine (chx) mouthwash on experimentally contaminated orthodontic elast...