نتایج جستجو برای:

تعداد نتایج: 89  

2011
Hai-Chuan Yu Hua-Lu Zhao Zhi-Kui Wu Jun-Wu Zhang

BACKGROUND Human globin gene expression is precisely regulated by a complicated network of transcription factors and chromatin modifying activities during development and erythropoiesis. Eos (Ikaros family zinc finger 4, IKZF4), a member of the zinc finger transcription factor Ikaros family, plays a pivotal role as a repressor of gene expression. The aim of this study was to examine the role of...

2016
Zhuoming Lu Xinhua Qian Chunhong Zhang Zhiwen Chen Guangliang Du

A previous study conducted by our group demonstrated that Radix Astragali compounded with Codonopsis pilosula and Plastrum testudinis was effective in treating pediatric β-thalassemia in a randomized, controlled clinical trial. However, the mechanism of action that underpins this treatment remains to be elucidated. Blood was collected from patients participating in this clinical trial and nucle...

2004
Ping Wang

The phase between three-gluon and one-photon amplitudes in ψ(2S) and ψ(3770) decays is analyzed. 1 Motivations It has been known that in J/ψ decays, the three gluon amplitude a3g and one-photon amplitude aγ are orthogonal for the decay modes 10 (90◦) [1], 1−0− (106 ± 10)◦ [2], 0−0− (89.6 ± 9.9)◦ [3], 1−1− (138± 37)◦ [4] and NN (89± 15)◦ [5]. J. M. Gérard and J. Weyers [6] augued that this large...

1994
Amitava Raychaudhuri

We investigate the impact of a light gluino, which might have escaped detection at colliders, on inclusive radiative B-decays mediated through penguin-like diagrams. We find that the viability of the scenario depends largely on the magnitude of the flavour-violating c-parameter. Some previously allowed regions of parameter space are now ruled out. PACS Nos: 14.80.Ly, 11.30.Pb, 13.40.Hq CERN-TH....

Journal: :American journal of human genetics 2017
Diyu Chen Yangjin Zuo Xinhua Zhang Yuhua Ye Xiuqin Bao Haiyan Huang Wanicha Tepakhan Lijuan Wang Junyi Ju Guangfu Chen Mincui Zheng Dun Liu Shuodan Huang Lu Zong Changgang Li Yajun Chen Chenguang Zheng Lihong Shi Quan Zhao Qiang Wu Supan Fucharoen Cunyou Zhao Xiangmin Xu

A delayed fetal-to-adult hemoglobin (Hb) switch ameliorates the severity of β-thalassemia and sickle cell disease. The molecular mechanism underlying the epigenetic dysregulation of the switch is unclear. To explore the potential cis-variants responsible for the Hb switching, we systematically analyzed an 80-kb region spanning the β-globin cluster using capture-based next-generation sequencing ...

2005
Kenji Fukushima

We calculate the Debye and Meissner masses and investigate chromomagnetic instability associated with the gapless color superconducting phase changing the strange quark mass Ms and the temperature T . Based on the analytical study, we develop a computational procedure to derive the screening masses numerically from curvatures of the thermodynamic potential. When the temperature is zero, from ou...

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