A random sample of 1,200 employees of a steel plant in the western United States was randomly assigned to four different self-report methods of assessing illicit drug use: individual interview in the workplace, group-administered questionnaire in the workplace, telephone interview, and individual interview off the worksite. Urine specimens were collected and analyzed on all 928 subjects partici...

Streptomyces sp. strain NTK 937 is the producer of the benzoxazole antibiotic caboxamycin, which has been shown to exert inhibitory activity against Gram-positive bacteria, cytotoxic activity against several human tumor cell lines, and inhibition of the enzyme phosphodiesterase. In this genome announcement, we present a draft genome sequence of Streptomyces sp. NTK 937 in which we identified at...

The CMU Example-Based Machine Translation (EBMT) system has been deployed successfully in many projects for years. But even though a good alignment algorithm is essential since the CMU EBMT system uses parallel corpora, it has relatively less studied than other components of EBMT. For this reason, we developed a new alignment algorithm which uses statistical information drawn from parallel corp...

Copyright: © 2015 Chen P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Corresponding author: Sangeeta Agrawal, Associate Professor of Medicine, Dept. of Internal Medicine, Division of Gastroenterolo...

Benzothiazolyl thiocarbamides has been achieved using a catalytic amount of 4-dimethylaminopyridine (DMAP) followed by its chemoselective oxidative cyclization with 1,3-di-n-butylimidazolium tribromide[bbim][Br(3)] to afford the N-bis-benzothiazole derivatives. All the synthesized compounds were evaluated for cytotoxic activity against two human monocytic cell lines (U 937, THP-1) and a mouse m...

This corrects the article on p. 928 in vol. 56, PMID: 26069113.

U-937 is a human monocytic cell line that has been to elaborate factors that affect normal human hematopoiesis in vitro. Studies on the effects of these factors demonstrated an erythroid potentiating factor (EPF) and a potent inhibitor of granulocyte-macrophage (CFU-GM) colony growth. The EPF was present in both serum-containing and serum-free U-937 conditioned media, had a dose-dependent effec...

Running Title: A Currents and the Chemosensitive Response of LC Neurons 19 20 21 Corresponding Author: Dr. Robert W. Putnam 22 Department of Neuroscience, Cell Biology and Physiology 23 Wright State University Boonshoft School of Medicine 24 3640 Colonel Glenn Highway 25 Dayton, OH 45435, USA 26 [email protected] 27 TEL: 01-937-775-2288 28 FAX: 01-937-775-3391 29 30 Articles in PresS. Am...

The human cell lines HL-60 (acute promyelocytic leukemia) and U-937 (histiocytic monoblast-like lymphoma) differentiate to functionally mature cells by incubation with retinoic acid (RA). This differentiation is potentiated by agents known to increase intracellular cyclic adenosine 3':5'-monophosphate (cAMP) levels. The present study shows that these cells can be primed for differentiation by t...

Macrolide antibiotics modulate the production of proinflammatory cytokines in vivo and in vitro. Transcription of the genes for these proinflammatory cytokines is regulated by nuclear factor kappaB (NF-kappaB). We examined whether or not clarithromycin inhibits the activation of NF-kappaB induced by tumor necrosis factor alpha (TNF-alpha) or staphylococcal enterotoxin A (SEA) in human monocytic...