Protein kinase D1 (PKD1) is a Ser/Thr kinase implicated in a wide variety of cellular responses. PKD1 activation is generally attributed to a PKC-dependent pathway that leads to phosphorylation of the activation loop at Ser(744)/Ser(748). This modification increases catalytic activity, including that toward an autophosphorylation site (Ser(916)) in a postsynaptic density-95/disks large/zonula o...

We have examined the role of protein kinase D1 (PKD1) signaling in intestinal epithelial cell migration. Wounding monolayer cultures of intestinal epithelial cell line IEC-18 or IEC-6 induced rapid PKD1 activation in the cells immediately adjacent to the wound edge, as judged by immunofluorescence microscopy with an antibody that detects the phosphorylated state of PKD1 at Ser(916), an autophos...

This paper describes the architecture and operation of a direct conversion transmitter for integration with the Bioluminescent Bioreporter Integrated Circuit (BBIC). The transmitter circuit is designed for 916 MHz frequencies. This system is made up of Phase Lock Loop (PLL), Gilbert Cell mixer, Power Amplifier and Antenna. The power amplifier is added to transmit the data in desired distance. S...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371 6.5 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 370 6.5 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 7.9 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 6.7 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....

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