Transcription factors are important targets for the treatment of a variety of malignancies but are extremely difficult to inhibit, as they are located in the cell’s nucleus and act mainly by protein-DNA and protein-protein interactions. The transcriptional regulators Id1 and Id3 are attractive targets for cancer therapy as they are required for tumor invasiveness, metastasis and angiogenesis. W...

ABST RACT The ideal treatment for pseudomyxoma peritonei is an active area of investigation with mounting evidence for the benefit of complete cytoreduction and hyperthermic intraperitoneal chemoperfusion (HIPEC). The unusual nature of this disease was demonstrated with a report of a patient with pseudomyxoma peritonei of appendiceal origin discovered thirty-two years after appendectomy. The re...

In vivo lung micro-computed tomography (micro-CT) is being increasingly embraced in pulmonary research because it provides longitudinal information on dynamic disease processes in a field in which ex vivo assessment of experimental disease models is still the gold standard. To optimize the quantitative monitoring of progression and therapy of lung diseases, we evaluated longitudinal changes in ...

white been line wa8592-1 was first introduced in iran through the yield trail nurseries received fron ciat in 1991. in observation nurseries carried out during 1992 and 1993 cropping seasons, ten bean populations were evaluated for yield and other characteristics, and 60 lines were selected. preliminary and advanced yield trails carried out for six years (1995-2000) in four locations khomein, e...

an experiment was conducted in the experimental field of seed and plant improvement institute in karaj for three consecutive cropping seasons, 2001-2003, to study the effects of eight different fertilizer treatments including some microelements on grain yield and protein content of a bread wheat cultivar pishtaz. the experiment was in a rcbd with three replications.eight fertilizer treatments w...

The research was aimed at analyzing the performance of winter potato under different nitrogen rates experimental fields College Agriculture, Central Agricultural University, Imphal. variety Kufri Sindhuri cultivated during seasons 2017-18 and 2018-19 three rates- 120 kgha-1 (N1), 100 (N2) 80 (N3) using drip irrigation. results indicated that plants fertilized with recorded maximum germination p...

Omnivorous Heteroptera constitute an important component of predatory guilds with high potential for biological control. Understanding the relative effects of plant feeding on the suppression of prey by omnivores could be an important element for improving biological control strategies. In the current paper, the effects of different plant food sources on the predation rate of the omnivorous pre...

Penicilliosis is a tropical disease occurring mostly in Southeast Asia. The incidence of Penicillium marneffei infection in acquired immunodeficiency syndrome (AIDS) patients is increasing due to the infection of the HIV in the population in recent years. In this report, the bone marrow smears of 331 AIDS patients have been examined for the evidence of P. marneffei infection, and 35 (10.6%) of ...