as nitric oxide (NO), superoxide anion (O2 ), hydroxyl ( ·OH) radicals and peroxynitrite (ONOO ), are toxic and play an important role in tissue injury. O2 reacts rapidly with NO to produce the more toxic ONOO . In addition, ONOO and its decomposition product, ·OH, contribute to antioxidant depletion, alterations of protein structure and oxidative damage observed in human diseases. Thus, it is ...

A double-masked study was conducted to determine the efficacy and safety of randomly allocated chenodiol (chenodeoxycholic acid, 750 mg/d or 350 mg/d) or placebo administered for 2 years to 916 patients for dissolution of radiolucent gallstones. There was confirmed complete dissolution in 13.5% of patients (750 mg/d), 5.2% (375 mg/d), and 0.8% (placebo), p less than 0.0001. Partial (over 50%) o...

The purpose of this study was to observe the effects of low doses of aflatoxin B1 (AFB1) on responses to common vaccines and levels of serum cations in broilers. Male broilers at 7 d of age were fed control (no AFB1), a 75 µg of AFB1/kg (75 ppb of AFB1) diet, or a 750 µg of AFB1/kg (750 ppb of AFB1) diet. The 750 ppb of AFB1 diet resulted in a temporary increase in ELISA titers against Newcastl...

We consider the possibility that the diphoton excess at 750 GeV is caused by a new scalar resonance produced in photon fusion. This scenario is parametrized by only one relevant effective couplings and is thus minimal. We show that this setup can reproduce both the production rate and width of the resonance, and is not in conflict with the 8 TeV limits on the diphoton cross section. The scenari...

for detecting organic and/or inorganic compounds and therefore it has been widely used in many scientific fields with improving analytical instruments such as high-performance liquid chromatography (HPLC), capillary electrophoresis (CE), fluorescence confocal microscopy, etc. For these purposes, a great deal of effort has gone into the development of fluorescent reagents using various fluoropho...

Di(n-butyl) phthalate (DBP), a widely used plasticizer suspected of having estrogenic properties, was investigated for its effects on the prenatal and early neonatal development of the reproductive tract. Pregnant CD rats (n = 10) were given DBP at 0, 250, 500, or 750 mg/kg/day (p.o.) throughout pregnancy and lactation until their offspring were at postnatal day 20. Maternal body weights throug...