We find that the formation of MWC 656 (the first Be binary containing a black hole) involves a common envelope phase and a supernova explosion. This result supports the idea that a rapidly rotating Be star can emerge out of a common envelope phase, which is very intriguing because this evolutionary stage is thought to be too fast to lead to significant accretion and spin up of the B star. We pr...

PERSPECTIVES ANDUMMARY .............................................................. 632 HSP110 .................................................................................................. 634 THE HSP 90 FAMILY .............................................................................. 634 Biochemical Analysis ..............................................................................

1 Department of Internal Medicine, Division of Medical Oncology, University Hospital, Zurich, Switzerland. 2 Department of Pharmacology, University of Bern, Bern, Switzerland * Corresponding authors: U Zangemeister-Wittke, Division of Medical Oncology, University Hospital, HaÈldeliweg 4, CH-8044 ZuÈrich. Tel: +41-1-634-2877; Fax: +41-1-634-2872; E-mail: [email protected] and H-U Simon...

The relationship between vascular endothelial growth factor gene polymorphism and gastric cancer risk and its development, prognosis, and survival are still being debated. This meta-analysis was performed to assess these relationships. The association reports were identified from PubMed, Embase, Cochrane Library, and CBM-disc (China Biological Medicine Database), and eligible studies were inclu...

يهدف هذا البحث إلى محاولة توضيح الدور الفاعل والإسهام اللامحدود الذي قام به عدد من القضاة العراقيون في تاريخ الدولة العربية الإسلامية عن طريق تنمية وتحديث بعض النظم القضائية التي ظلّت على حالها حتى مجيء قضاة (عراقيين) أكفّاء لاسيما العصر العباسي، تعود اليه الجذور الأولى لظهور منصب قاضي ، وأن النضوج الحقيقي للنظام القضائي شهد تنوعاَ تطبيق الأحكام استناداً المذاهب المعروفة كانت الى نفس المدة ومن هنا ...

Some tumor-suppressing miRNAs target multiple oncogenes concurrently and therefore may be useful as cancer therapeutic agents. Further, such miRNAs may be useful to address chemotherapeutic resistance in cancer, which remains a primary clinical challenge in need of solutions. Thus, cytoprotective processes upregulated in cancer cells that are resistant to chemotherapy are a logical target for i...

We conducted a case-control study to investigate whether vascular endothelial growth factor (VEGF -2578, -1154, -634, and 936) and kinase insert domain containing receptor (KDR -604, 1192, and 1719) polymorphisms are associated with moyamoya disease. Korean patients with moyamoya disease (n = 107, mean age, 20.9±15.9 years; 66.4% female) and 243 healthy control subjects (mean age, 23.0±16.1 yea...

Thymidylate synthase (TS) functions as an RNA-binding protein by interacting with two different sequences on its own mRNA. One site is located in the 5'-upstream region of human TS mRNA while the second site is located within the protein coding region corresponding to nt 434-634. In this paper, a 70 nt RNA sequence, corresponding to nt 480-550, was identified that binds TS protein with an affin...