نتایج جستجو برای: 608

تعداد نتایج: 2267  

2009
Richard E Connon Juergen Geist Janice Pfeiff Alexander V Loguinov Leandro S D'Abronzo Henri Wintz Christopher D Vulpe Inge Werner

Background: The delta smelt (Hypomesus transpacificus) is a pelagic fish species listed as endangered under both the USA Federal and Californian State Endangered Species Acts and considered an indicator of ecosystem health in its habitat range, which is limited to the SacramentoSan Joaquin estuary in California, USA. Anthropogenic contaminants are one of multiple stressors affecting this system...

2014
Juozas Kupcinskas Indre Bruzaite Simonas Juzenas Ugne Gyvyte Laimas Jonaitis Gediminas Kiudelis Jurgita Skieceviciene Marcis Leja Henrikas Pauzas Algimantas Tamelis Dainius Pavalkis Limas Kupcinskas

Colorectal cancer (CRC) is one of the most common cancers worldwide with high mortality rates. MicroRNAs (miRNAs) have an established role in the development of different cancers. Single nucleotide polymorphisms (SNPs) in miRNA related genes were linked with various gastrointestinal malignancies. However, the data on association between miRNA SNPs and CRC development are inconsistent. The aim o...

Journal: :Cancer research 2013
Jian Zheng Jieqiong Deng Mang Xiao Lei Yang Liyuan Zhang Yonghe You Min Hu Na Li Hongchun Wu Wei Li Jiachun Lu Yifeng Zhou

Nasopharyngeal carcinoma is treated with radiotherapy and other modalities, but there is little information on individual genetic factors to help predict and improve patient outcomes. Single-nucleotide polymorphisms (SNP) in mature microRNA (miRNA) sequences have the potential to exert broad impact as miRNAs target many mRNAs. The aim of this study was to evaluate the effects of SNPs in mature ...

Journal: :Journal of Investigative Dermatology 2022

Commonly associated with pregnancy, stretchmarks appear whenever the body experience a rapid growth. Into dermis, collagen fibres are altered loss of orientation and elastic network is disrupted leading to fibrotic organisation. This results epidermal tearing which produce skin lesions. Centella asiatica one most well-known medicinal plants rich in triterpenic actives molecules traditionally us...

Journal: :Annals of neurology 2016
Rebecca Schüle Sarah Wiethoff Peter Martus Kathrin N Karle Susanne Otto Stephan Klebe Sven Klimpe Constanze Gallenmüller Delia Kurzwelly Dorothea Henkel Florian Rimmele Henning Stolze Zacharias Kohl Jan Kassubek Thomas Klockgether Stefan Vielhaber Christoph Kamm Thomas Klopstock Peter Bauer Stephan Züchner Inga Liepelt-Scarfone Ludger Schöls

OBJECTIVE Hereditary spastic paraplegias (HSPs) are genetically driven disorders with the hallmark of progressive spastic gait disturbance. To investigate the phenotypic spectrum, prognostic factors, and genotype-specific differences, we analyzed baseline data from a continuous, prospective cohort. METHODS We recruited 608 HSP cases from 519 families of mostly German origin. Clinical severity...

Journal: :Molecular medicine reports 2014
Rui Wang Jun Zhang Yanyun Ma Linqi Chen Shicheng Guo Xiaojiao Zhang Yunfang Ma Lijun Wu Xiaoyu Pei Siran Liu Jiucun Wang Heping Hu Jie Liu

Polymorphisms in pre‑microRNAs (miRNAs) or mature miRNAs may influence miRNA processing or target binding, thus contributing to tumorigenesis and cancer development. The present study aimed to evaluate whether miR‑149 rs2292832 (C>T) and miR‑608 rs4919510 (G>C) are associated with the risk and clinical characteristics of hepatocellular carcinoma (HCC) in a large‑scale population. miR‑149 rs2292...

2013
Jian Zheng Jieqiong Deng Mang Xiao Lei Yang Liyuan Zhang Yonghe You Min Hu Na Li Hongchun Wu Wei Li Jiachun Lu Yifeng Zhou

Nasopharyngeal carcinoma is treated with radiotherapy and other modalities, but there is little information on individual genetic factors to help predict and improve patient outcomes. Single-nucleotide polymorphisms (SNP) in mature microRNA (miRNA) sequences have the potential to exert broad impact as miRNAs target many mRNAs. The aim of this study was to evaluate the effects of SNPs in mature ...

2017
Huiquan Liu Yaqun Zhou Qingquan Liu Guangqin Xiao Bangyan Wang Weijuan Li Dawei Ye Shiying Yu

Single nucleotide polymorphisms (SNPs) in MicroRNAs (miRNAs) are involved in the mechanism of carcinogenesis. Several studies have evaluated the association of rs4919510 SNP in miR-608 with cancer susceptibility in different types of cancer, with inconclusive outcomes. To obtain a more precise estimation, we carried out this meta-analysis through systematic retrieval from the PubMed and Embase ...

2011
Summer M. Raines Oliver C. Richards Lindsay R. Schneider Kathryn L. Schueler E. Rabaglia Angie T. Oler Donald S. Stapleton Guillem Genové John A. Dawson Alan D. Attie

Running title: PDGF-B deficiency enhances insulin sensitivity 5 6 Summer M. Raines, Oliver C. Richards, Lindsay R. Schneider, Kathryn L. Schueler, Mary 7 E. Rabaglia, Angie T. Oler, Donald S. Stapleton, Guillem Genové, John A. Dawson, Christer 8 Betsholtz, and Alan D. Attie 9 10 11 Department of Biochemistry; University of Wisconsin-Madison; Madison, WI 53706 12 Graduate Program in Cellular and...

Journal: :Kvinder, køn & forskning 2021

Simone de Beauvoir:Det andet køn, Bind I. Kendsgerninger og Myter & II. Erfaringer oplevelser.Gyldendal, 2019, 388 hhv. 608 sider. Pris: 350 kr. Oversat fra fransk af Karen Stougaard Hansen, Svend Johansen Mette Olesen. Revideret Claus Clausen.

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