This work evaluated the process for heptaldehyde, undecylenic acid and methyl undecenoate production from castor oil, ester of oil ricinoleic acid. Experiments were performed in a continuous pilot-plant scale pyrolysis reactor. Those are very important green chemical products that might be obtained by thermal cracking oil. Transesterification produces ricinoleate its generates heptaldehyde. The...

ABT-493 is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor, and ABT-530 is an HCV NS5A inhibitor. These direct-acting antivirals (DAAs) demonstrated potent antiviral activity against major HCV genotypes and high barriers to resistance in vitro. In this open-label dose-ranging trial, antiviral activity and safety were assessed during 3 days of monotherapy with ABT-49...

The detection and quantification of Plasmodium falciparum in studies of malaria endemicity primarily relies upon microscopy. High-throughput quantitative methods with less subjectivity and greater reliability are needed for investigational studies. The staining of parasitized erythrocytes with YOYO-1 for flow cytometry bears great potential as a tool for assessing malaria parasite burden. Capil...

A variety of drugs inhibit the conversion of arachidonic acid to prostaglandin G2 by the cyclooxygenase (COX) activity of prostaglandin endoperoxide synthases. Several modes of inhibitor binding in the COX active site have been described including ion pairing of carboxylic acid containing inhibitors with Arg-120 of COX-1 and COX-2 and insertion of arylsulfonamides and sulfones into the COX-2 si...

The following robust detection problem is considered in this note. The nominal signals are known, but the actual signals present in the observed data can be corrupted slightly. The probability distribution of the noise is known precisely, or some small deviation exists from the nominal model. To derive the robust detector which is insensitive to the corruption of signals and deviation from nomi...

Abstract. We present images of NRAO530 observed with the EVN (VLBI) at 5 GHz, the MERLIN at 1 .6 and 5 GHz, and the VLA at 5 and 8 GHz showing the complex morphology on scales from pc to kpc. The VLBI image shows a core-jet structure indicating a somehow oscillation trajectory on a scale of 30 mas, north to the strongest compact component (core). A core-jet structure extended to several hundred...