A randomized trial was conducted to test the effectiveness of couple-based HIV counseling and testing (CB-HIV-CT) and women-only relationship-focused HIV counseling and testing (WRF-HIV-CT) in reducing HIV risk compared to the National Institute on Drug Abuse HIV-CT standard intervention. Substance using HIV-negative women and their primary heterosexual partner (N = 330 couples) were randomized...

D-Galactosamine/Lipopolysaccharide (D-GalN/LPS) is a well known model of hepatotoxicity that closely resembles acute liver failure (ALF) seen clinically. The role of sirtuin 1 in this model has not yet been documented. However, there have been a number of studies about the cytoprotective effects of resveratrol, a SIRT1 activator, in the liver. This study was aimed at elucidating the roles of SI...

In C4 plants, pyruvate orthophosphate dikinase (PPDK) activity is tightly dark/light regulated by reversible phosphorylation of an active-site threonine (Thr) residue; this process is catalyzed by PPDK regulatory protein (PDRP). Phosphorylation and dephosphorylation of PPDK lead to its inactivation and activation, respectively. Here, we show that light intensity rather than the light/dark trans...

This essay looks at the historical significance of three APS classic papers that are freely available online: Gottschalk CW and Mylle M. Micropuncture study of the mammalian urinary concentrating mechanism: evidence for the countercurrent hypothesis. Am J Physiol 196: 927–936, 1959 (http://ajplegacy.physiology.org/cgi/reprint/196/4/927). Ullrich KJ, Schmidt-Nielsen B, O’Dell R, Pehling G, Gotts...

Appears in: ICERI2022 Proceedings Publication year: 2022Pages: 527-536ISBN: 978-84-09-45476-1ISSN: 2340-1095doi: 10.21125/iceri.2022.0172Conference name: 15th annual International Conference of Education, Research and InnovationDates: 7-9 November, 2022Location: Seville, Spain

A survey of trematode larvae in the fresh water snail, Bithynia goniomphalos in the main water reservoir of Huai Thalaeng district, Nakhon Ratchasima Province, Thailand, was conducted. The study site is in an area with a high prevalence of Opisthorchis viverrini infection. Malacological samplings were made during the year 2000 to study the prevalence and intensity of infection. Parasitological ...

The compression of 300-fs-long, chirp-free laser pulses at 527 nm down to 30 fs is reported. The laser pulses, originated from a frequency-doubled, mode-locked Nd:glass laser, were compressed by a 0.7-m-long, 150-microm-bore-diameter, argon-filled hollow fiber, and a pair of SF10 prisms with a final energy of 160 microJ. These are the shortest, high energy pulses ever produced by direct pulse c...

Protein-tyrosine kinases play pivotal roles in cell signal transduction. We have isolated a cDNA clone encoding a novel human intracytoplasmic tyrosine kinase, termed matk (megakaryocyte-associated tyrosine kinase). Expression of matk mRNA was predominantly found in cells of megakaryocytic lineage. The matk cDNA clone encodes a polypeptide of 527 amino acids and has closest sequence similarity ...