General. All reactions were performed under argon using Schlenk techniques. Diethyl ether and THF were freshly distilled from sodium/benzophenone prior to use. 1 H, 13 C and 31 P spectra were recorded on a 400 MHz and 300 MHz spectrometers. Chemical shifts (ppm) were reported and referenced to the internal signal of residual protic solvent. High resolution mass spectral analyses (HRMS) were per...

5 Longsheng Xu 1, , Yanyan Pan , Qi Zhu , Shan Gong , Jin Tao , Guang-Yin Xu 1, , 6 Xinghong Jiang 1 * 7 8 1 Key Laboratory of Pain Basic Research & Clinical Therapy, Department of Neurobiology, 9 Medical College of Soochow University, Suzhou 215123, China; 10 2 Institute of Neuroscience, Soochow University, Suzhou 215123, China; 11 3 The First Hospital of Jiaxing, Jiaxing 314000, Zhejiang, Chi...

Since neurovascular control is altered in obese subjects, we hypothesized that weight loss by diet (D) or diet plus exercise training (D + ET) would improve neurovascular control during mental stress in obese women. In a study with a dietary reduction of 600 kcal/day with or without exercise training for 4 months, 53 obese women were subdivided in D (N = 22, 33 +/- 1 years, BMI 34 +/- 1 kg/m2),...

The purpose of this study was to determine the optimal timing of intravenous glucagon infusion for the treatment of acute occlusive mesenteric ischemia. The superior mesenteric artery (SMA) was occluded for 85 min in 106 Sprague-Dawley anesthetized rats. The animals were divided into 12 treatment groups according to the timing of glucagon and saline administration, and survival was measured to ...

In a 4 × 4 Latin square design (24-d periods), 4 ruminally cannulated Hereford × Angus/ Simmental heifers were used to evaluate the effect of increasing levels of monensin concentration on DMI, ruminal fermentation, short-chain fatty acid (SCFA) absorption across the reticulorumen, and total tract barrier function. Heifers were fed a barley-based finishing diet (76% rolled barley grain, 12% bar...

Telomerase activation has very important implications for head and neck squamous cell carcinoma (HNSCC), but the regulatory mechanisms of telomerase in HNSCC remain unclear. In our present study, we found that miR-512-5P was markedly downregulated in telomerase-positive HNSCC cell lines. Both in vitro and in vivo assays revealed that miR-512-5P mimic attenuated HNSCC cell proliferation, and tum...

In this article, a deep artificial neural network (ANN) model has been proposed to predict the boiling heat transfer in helical coils under high gravity conditions, which is compared with experimental data. A test rig set up provide 11 g flux 15100 W/m2 and mass velocity range from 40 2000 kg m−2 s−1. current work, total 531 data samples have used ANN model. The was developed Python Keras envir...

Neuropathic pain after nerve injury is severe and intractable, and current drugs and nondrug therapies offer substantial pain relief to no more than half of affected patients. The present study investigated the analgesic roles of the B vitamins thiamine (B1), pyridoxine (B6) and cyanocobalamin (B12) in rats with neuropathic pain caused by spinal ganglia compression (CCD) or loose ligation of th...

P wave centric ambulatory electrocardiographic (ECG) monitoring has emerged as an important tool aiding the diagnosis of arrhythmias. However, their efficacy and user experience in infants young children are not well established. A retrospective study was performed to detail clinical ECG using Carnation Ambulatory Monitor (CAM) patch (Bardy Diagnostics Inc., Seattle, WA) patients less than 10 k...