Anti-nociceptive efficacy of carprofen and meloxicam was evaluated in twelve female dogs brought for elective ovariohysterectomy randomly assigned to Group A and Group B. In Group A Carprofen was administered @ 4 mg/kg i.v, whereas in Group B, Meloxicam was administered @ 0.2 mg/ kg i.v, immediately after completion of surgery. Pain scores decreased significantly following analgesia with carpro...

BACKGROUND The benefit of pre and post-operative administration of non-steroidal anti-inflammatory drugs for the relief of post-operative pain and control of inflammation in horses following orthopaedic surgery has not been previously investigated in controlled clinical field trials, and the utility of such treatment is a matter of ongoing dispute. Recently the utility of post-operative pain ma...

Dehorning is a painful husbandry procedure that is commonly performed in dairy calves. Parenteral meloxicam combined with local anesthesia mitigates the physiological and behavioral effects of dehorning in calves. The purpose of this study was to determine the influence of timing of oral meloxicam administration on physiological responses in calves after dehorning. Thirty Holstein bull calves, ...

Cerebral vasospasm considered to be a serious cause of morbidity and mortality following subarachnoid haemorrhage (SAH).Despite several available therapeutic options, current protocols do not prevent major consequences of vasospasm. Inflammation is believed to play an important role in post-haemorrhagic vasospasm. Meloxicam is a non-steroidal anti-inflammatory drug. The aim of this study was to...

Cyclooxygenase (COX)-2 expression is positively correlated with malignant features in canine mammary carcinomas. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX activity and may therefore possess anticancer effects. Meloxicam is an NSAID that is widely used in human and veterinary medicine. High concentrations of meloxicam have been reported to be antitumorigenic in vitro; however, t...

Cerebral vasospasm considered to be a serious cause of morbidity and mortality following subarachnoid haemorrhage (SAH).Despite several available therapeutic options, current protocols do not prevent major consequences of vasospasm. Inflammation is believed to play an important role in post-haemorrhagic vasospasm. Meloxicam is a non-steroidal anti-inflammatory drug. The aim of this study was to...

BACKGROUND Cyclooxygenase (COX)-2 is overexpressed in many types of cancers including hepatocellular carcinoma (HCC). Meloxicam, a selective COX-2 inhibitor, has shown potential therapeutic effects against HCC, but the mechanisms accounting for its anti-cancer activities remain unclear. METHODS AND FINDINGS Meloxicam inhibited the ability of human HCC cells expressing higher levels of COX-2 t...

This study was conducted to evaluate and compare the clinical, hemato-biochemical endoscopic aspects of gastropathy in dogs treated with meloxicam alone or incombination esomeprazole misoprostol. Twenty baladi healthy were included experimental study. Dogs divided into four groups each group consisting five animals; Group I (control group), that does not receive any medication. Meloxicam into: ...