نتایج جستجو برای: 46 xy female

تعداد نتایج: 351927  

2016
Sorahia Domenice Aline Zamboni Machado Frederico Moraes Ferreira Bruno Ferraz‐de‐Souza Antonio Marcondes Lerario Lin Lin Mirian Yumie Nishi Nathalia Lisboa Gomes Thatiana Evelin da Silva Rosana Barbosa Silva Rafaela Vieira Correa Luciana Ribeiro Montenegro Amanda Narciso Elaine Maria Frade Costa John C Achermann Berenice Bilharinho Mendonca

Steroidogenic factor 1 (NR5A1, SF-1, Ad4BP) is a transcriptional regulator of genes involved in adrenal and gonadal development and function. Mutations in NR5A1 have been among the most frequently identified genetic causes of gonadal development disorders and are associated with a wide phenotypic spectrum. In 46,XY individuals, NR5A1-related phenotypes may range from disorders of sex developmen...

Journal: :Journal of medical genetics 1973
G E Sarto J M Opitz

A patient with a 46,XY chromosome constitution showed the following main characteristics: eunuchoidal body habitus, lack of secondary sexual development, normal female external genitalia with absence of vagina, no gonadal structures, and complete lack of internal genitalia except for rudimentary ductal structures defined by histological examination. Her condition is clearly different from that ...

2003
M. S. ADAMS JOHN L. HAMERTON

SIR,-In a recent review de Grouchy 1 compiles the following karyotypes described in true hermaphroditism: 46 XX, 46 XY, 46 XX/46 XY, 45 XO/46 XY, 46 XX/47 XXY, 46 XX/47 XXX, 46 XX/46 XY/45 XO, 46 XX/47 XXY/ 49 XXYYY, and 45 XO/46 X isoY/47 XY isoY. We have studied the chromosomes of a true hermaphrodite with a new mosaicism, 46 XX/46 XY/47 XXY, which might throw some light on the possible multi...

Journal: :Archives of disease in childhood 1990
K Walker A J Gunn P D Gluckman

Eight cases of 45 XO/46 XY mosaicism are described: four were phenotypic males. Karyotyping should be performed more frequently in short boys as growth hormone treatment and testicular biopsy, to screen for carcinoma in situ, are likely to be beneficial.

2017
Yu Mao Shaoji Chen Ru Wang Xuejun Wang Daorui Qin Yunman Tang

BACKGROUND The aim of this study is to review and present the clinical features and process of evaluation and treatment for OT-DSD in a single center in recent years in China. METHODS Sixteen patients with OT-DSD during the past 4 years underwent the evaluation and treatment in a single center. The clinical characteristics and outcomes of surgery were analyzed. RESULTS The surgical age rang...

2016
MingShan Liu Munawar Iqbal Christoph Peter Hauri

We present measurements and analysis of the longitudinal timing jitter of a Beijing Electron Positron Collider (BEPCII) linear accelerator electron gun. We simulated the longitudinal jitter effect of the gun using PARMELA to evaluate beam performance, including: beam profile, average energy, energy spread, and XY emittances. The maximum percentage difference of the beam parameters is calculated...

2016
Alexander Muacevic John R Adler Naveen P Kumar Venugopal M Anitha Mathews Francis V James

Swyer syndrome or pure gonadal dysgenesis 46, XY is a medical condition associated with 46 XY karyotype and primary amenorrhea in a phenotypic female. In this syndrome, there is an abnormality in testicular differentiation. Patients with disorders in sexual differentiation have an increased risk for development of genital malignancies. A 14-year-old female admitted with abdominal pain was diagn...

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