Intravenous injection of substance P (SP) increases renal nerve firing and heart rate in spontaneously hypertensive rats (SHRs) and Wistar-Kyoto rats (WKYs) by stimulating sympathetic ganglia. Blood pressure is increased in SHRs but lowered in WKYs. This study assesses the role of neurokinin-1 (NK(1)) receptors in mediating the ganglion actions of SP. Rats for functional studies were anesthetiz...

The effect of formoterol, alone and in combination with budesonide, upon tumour necrosis factor-alpha stimulated (10 ng x mL(-1)) human bronchial epithelial cells was investigated. Addition of formoterol (> or = 10(-10) M) reduced granulocyte macrophage-colony stimulating factor (GM-CSF) levels, as assessed by enzyme-linked immunosorbent assay, by 40-50% and increased interleukin (IL)-8 levels ...

Soap is a product from the hydrolysis of fats into fatty acids and glycerol under alkaline conditions, known as saponification process. Many factors affect process to produce liquid soap with proper quality, including viscosity density values. Saponification time stirring speed are that quality be observed. Using strong bases electrolysis machines well coconut oil natural comperland innovations...

Each Gr-functor of the type (φ, f) of a Gr-category of the type (Π, C) has the obstruction be an element k ∈ H(Π, C). When this obstruction vanishes, there exists a bijection between congruence classes of Gr-functors of the type (φ, f) and the cohomology group H(Π,C). Then the relation of Gr-category theory and the group extension problem can be established and used to prove that each Gr-catego...

1 Yinnon AM, Hadas-Halpern I, Shapiro M, et al. The changing clinical spectrum of liver abscess: the Jerusalem experience. Postgrad Med J 1994; 70: 436-9. 2 Rubinson HA, IshikoffMB, Hill, MC. Diagnostic imaging of hepatic abscess: a retrospective analysis. AJR 1980; 135: 735-40. 3 McDonald MI, Corey GR, Gallis HA, et al. Single and multiple pyogenic liver abscess. Medicine 1984; 63: 291-302. 4 ...

In Wistar rats, hexachlorobenzene (HCB) depresses the gluconeogenic enzyme phosphoenolpyruvate-carboxykinase (PEPCK). In the liver, glucocorticoids (GC) normally regulate the glucose synthesis by acting on PEPCK. Thus, the aim of this work was to investigate, in a time-course study, the effects of HCB on plasma GC, its adrenal synthesis and stimulation, and the kinetic parameters of its hepatic...

Modulation of glucocorticoid receptor expression in human bronchial epithelial cell lines by IL-1β, TNF-α and LPS. M.M. Verheggen, P.Th.W. van Hal, P.W.C. AdriaansenSoeting, B.J.A. Goense, H.C. Hoogsteden, A.O. Brinkmann, M.A. Versnel. ERS Journals Ltd 1996. ABSTRACT: Bronchial epithelium plays a major role in the regulation of inflammatory reactions in the airways. It is thought to be a possi...