Many environmental chemicals and pesticides have been found to be estrogenic and have been shown to stimulate the growth of estrogen receptor-positive (ER-positive) human breast cancer cells. Since it is difficult to avoid human exposure to environmental estrogens, a potentially important area of research is the development of dietary strategies to prevent the stimulated growth of breast tumors...

Nonylphenol (NP) is an endocrine disrupting chemical which has been shown to be able to modulate endocrine system of various organisms by different mechanisms. The objective of this study was to investigate the potential effects of  4-NP and 17-β-estradiol (E2) on immune parameters (IgM level and lysozyme activity) of   Koi carp (Cyprinus the carpio carpio)  in an attempt to expand the knowledg...

Estradiol and 4-nonylphenol exposure studies in zebrafish. Approximately eighty male zebrafish were divided evenly between three 80 L glass aquaria. Each aquarium was individually heated to maintain a temperature of 26 /29 °C with a light-dark cycle ratio of 14:10 h. Fish were acclimated for one week prior to commencing the experiment. One tank contained only tap water (negative control) and th...

gene expression in juvenile rainbow trout. Short title: Effects of 4-n-nonylphenol and tamoxifen on gene expression in trout. Summary Alkylphenols such as nonylphenol (NP) are one of a wide variety of environmental chemicals reported to have estrogenic effects in both in vitro and in vivo studies. Induction of hepatic vitellogenin (Vg) gene expression is widely used as a biomarker for xenoestro...

Introduction: In this study, the effect of para-nonylphenol as an environmental pollutant on viability, morphology and proliferation of bone marrow mesenchymal stem cells was investigated. Methods: Bone marrow mesenchymal stem cells of rat were treated with the 0.5, 1, 2.5, 3.5 and 5 μM of paranonylphenol for a period of 21 days, then the viability of the cells were estimated using trypan bl...

In this work, the degradation of anionic and non-ionic surfactants in agricultural soil amended with sewage sludge is reported. The compounds analysed were: linear alkylbenzene sulphonates (LAS) with a 10-13 carbon alkylic chain, and nonylphenolic compounds (NPE), including nonylphenol (NP) and nonylphenol ethoxylates with one and two ethoxy groups (NP1EO and NP2EO). The degradation studies wer...