نتایج جستجو برای: 4 hydroxy 2 nonenal

تعداد نتایج: 3126698  

2008
Dae Yeon Kang Ji Young Lee Min-Sun Kim Chul Hong Kim Hyung Keun Kim Sun Mi Lee Jaewon Lee Byung Pal Yu Hae Young Chung

Young Mi Kwon, Jaewon Lee, Hyung Suk Baik, Byung Pal Yu and Hae Young Chung* College of Pharmacy, Pusan National University, Busan 609-735, Korea MRC for Ischemic Tissue Regeneration, College of Medicine, Pusan National University, Busan 602-739, Korea 3 Genetic Engineering Research Institute, Pusan National University, Busan, 609-735, Korea Department of Physiology, The University of Texas Hea...

Journal: :The Biochemical journal 1986
W Jessup G Jurgens J Lang H Esterbauer R T Dean

The incorporation of the lipid peroxidation product 4-hydroxynonenal into low-density lipoprotein (LDL) increases the negative charge of the particle, and decreases its affinity for the fibroblast LDL receptor. It is suggested that this modification may occur in vivo, and might promote atherogenesis.

Journal: :The Biochemical journal 2003
Rafał Sawicki Sharda P Singh Ashis K Mondal Helen Benes Piotr Zimniak

From the fruitfly, Drosophila melanogaster, ten members of the cluster of Delta-class glutathione S-transferases (GSTs; formerly denoted as Class I GSTs) and one member of the Epsilon-class cluster (formerly GST-3) have been cloned, expressed in Escherichia coli, and their catalytic properties have been determined. In addition, nine more members of the Epsilon cluster have been identified throu...

Bibhas Pandit Subrata Chakraborty Sumit Das Supratim Ray,

       The study was designed with an aim to evaluate the protective effects of reduced glutathione on cyclophosphamide induced lipid peroxidation and also changes in cholesterol content. Goat liver and white New Zealand rabbit were used as lipid source for the models. Lipid peroxidation study was performed by measuring the malondial...

Journal: :Acta poloniae pharmaceutica 2005
Santanu Chakraborty Pritesh Dev Bhuti Supratim Ray Chandana Sengupta Kunal Roy

4-Hydroxy-2-nonenal, an indicator of lipid peroxidation process. was used as model marker to explore ceftriaxone-induced lipid peroxidation in goat liver homogenate. Ceftriaxone was found to induce lipid peroxidation significantly. It was further found that ascorbic acid could significantly arrest ceftriaxone-induced lipid peroxidation. The results corroborate the earlier findings with malondia...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز 1357

در این کار پژوهش بیشتر سنتز ترکیبهای مختلف سه حلقه ای فنل با یک نوع هالوژن و هالوژنهای مختلف و کندن برم از آنها موردنظر است و مشتقهای مختلف از این نوع ترکیبات که در زیر شرح داده شده است سنتز گردیده است . علاوه براین از روشهای سنتزی برای تائید ساختمان ترکیبهای سه حلقه ای استفاده شده است . همچنین سنتز این ترکیبها امکان میدهد که خواص بیولوژیکی و شیمیائی آنها با ترکیبات مشابه دوحلقه ای و چهارحلقه ا...

2013
Corinne M. Spickett

4-Hydroxy-2-nonenal (HNE) is one of the most studied products of phospholipid peroxidation, owing to its reactivity and cytotoxicity. It can be formed by several radical-dependent oxidative routes involving the formation of hydroperoxides, alkoxyl radicals, epoxides, and fatty acyl cross-linking reactions. Cleavage of the oxidized fatty acyl chain results in formation of HNE from the methyl end...

Journal: :iranian journal of pharmaceutical sciences 0
supratim ray division of pharmaceutical chemistry, dr. b c roy college of pharmacy and allied health sciences, bidhannagar, durgapur, 713 206, india bibhas pandit division of pharmaceutical chemistry, himalayan pharmacy institute, majhitar, rangpo, east sikkim, 737 136, india sumit das division of pharmaceutical chemistry, himalayan pharmacy institute, majhitar, rangpo, east sikkim, 737 136, india subrata chakraborty division of pharmaceutical chemistry, dr. b c roy college of pharmacy and allied health sciences, bidhannagar, durgapur, 713 206, india

the study was designed with an aim to evaluate the protective effects of reduced glutathione on cyclophosphamide induced lipid peroxidation and also changes in cholesterol content. goat liver and white new zealand rabbit were used as lipid source for the models. lipid peroxidation study was performed by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide con...

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