نتایج جستجو برای: 4 h1
تعداد نتایج: 1314336 فیلتر نتایج به سال:
Epigenetic silencing in mammals involves DNA methylation and posttranslational modifications of core histones. Here we show that the H1 linker histone plays a key role in regulating both DNA methylation and histone H3 methylation at the H19 and Gtl2 loci in mouse ES cells. Some, but not all, murine H1 subtypes interact with DNA methyltransferases DNMT1 and DNMT3B. The interactions are direct an...
Bachmann, O., T. Sonnentag, W.-K. Siegel, G. Lamprecht, A. Weichert, M. Gregor, and U. Seidler. Different acid secretagogues activate different Na1/H1 exchanger isoforms in rabbit parietal cells. Am. J. Physiol. 275 (Gastrointest. Liver Physiol. 38): G1085–G1093, 1998.—Rabbit parietal cells express three Na1/H1 exchanger isoforms (NHE1, NHE2, and NHE4). We investigated the effects of carbachol,...
BACKGROUND H1/IC31® is a tuberculosis (TB) subunit vaccine candidate consisting of the fusion protein of Ag85B and ESAT-6 (H1) formulated with the IC31® adjuvant. Previous trials have reported on the H1/IC31® vaccine in M. tuberculosis (Mtb)-naïve, BCG-vaccinated and previously Mtb-infected individuals. In this trial, conducted between December 2008 and April 2010, the safety and immunogenicity...
در این تحقیق سعی شده است برای سنتز 1و2و4- اکسادیازول ها (آ)، 3- متیل- 4- آریل متیلن ایزوکسازول- 5(h4)- اون ها (ب) و 5- (r)-h1- تترازول ها (ث) از کاتالیزور سبز و کارآمد 4- (دی متیل آمینو) پیریدینیوم استات با مشخصه های مایعات یونی استفاده شود. همچنین 5- (r)-h1- تترازول(ج) در حضور کاتالیزور پی پرازینیوم دی هیدروژن سولفات در دمای 100 درجه سانتی گراد و در بازدهی بالا سنتز شد. و در نهایت تری آریل- ...
Both ZEUS and H1 have recently reported an excess of events at high Q and high Bjorken–x. However, the x distributions differ considerably; moreover, H1 sees more events with lower luminosity. Taken separately, the x distributions and the number of observed events are consistent between the two experiments at the few percent level. However, when combined it becomes clear that the results of H1 ...
We defined the epitopes recognized by three influenza A virus-specific, H-2Kd-restricted CD8(+) cytotoxic T-lymphocyte (CTL) clones: H1-specific clone A-12, H2-specific clone F-4, and H1- and H2-cross-reactive clone B7-B7. The A-12 and B7-B7 clones recognized the same peptide, which comprises amino acids 533 to 541 (IYSTVASSL) of A/PR/8 hemagglutinin (HA). The F-4 and B7-B7 clones both recogniz...
The main theorem of this paper states that ifM is a closed orientable hyperbolic 3-manifold of volume at most 3.08, then the dimension of H1(M ;Z2) is at most 7, and that it is at most 6 unless M is “strange.” To say that a closed, orientable 3-manifold M , for which H1(M ;Z2) has dimension 7, is strange means that the Z2-vector space H1(M ;Z2) has a 2-dimensional subspace X such that for every...
In this work we consider a model for particle dark matter where an extra inert Higgs doublet and an additional scalar singlet is added to the Standard Model (SM) Lagrangian. The dark matter candidate is obtained from only the inert doublet. The stability of this one component dark matter is ensured by imposing a Z2 symmetry on this additional inert doublet. The additional singlet scalar has a v...
Both ZEUS and H1 have recently reported an excess of events at high Q and high Bjorken–x. However, the x distributions differ considerably; moreover, H1 sees more events with lower luminosity. Taken separately, the x distributions and the number of observed events are consistent between the two experiments at the few percent level. However, when combined it becomes clear that the results of H1 ...
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