Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...

The objective of this study was to search for single nucleotide polymorphism (SNP)-type polymorphisms in the dopamine D1 receptor in West Azerbaijani native chicken and look for their association with egg production and body weight traits of chickens by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP). For this purpose 180 blood samples were taken from nativ...

BACKGROUND/AIMS Spinal tuberculosis (TB) is a common and dangerous form of extrapulmonary TB with unclear mechanisms in its occurrence and progression. This study investigated the clinical significances of bone morphogenetic protein-4 (BMP-4), osteopontin (OPN), and vitamin D receptor (VDR) gene polymorphism, mRNA and protein expression in spinal TB patients. METHODS BMP-4 and OPN gene polymo...

background: an association between lung cancer and chemokines has been advocated in the recent years. this study aims at investigating the association between lung cancer and 16c/a single nucleotide polymorphism (snp) (rs. 4359426) in c-c motif chemokine 22 (ccl22) as well as c1014t snp (rs. 2228428) in c-c chemokine receptor type 4 (ccr4), which serves as the receptor for ccl22. methods: genot...

in this report, β-tubulin gene polymorphism was investigated in haemonchus contortus  populations isolated from sheep flocks in different regions of khouzestan province, southwestern iran. the samples were chosen on the basis of regional variation in benzimidazole treatment background of sheep flocks. our objective was to study the relationship between treatment background andβ -tubulin gene po...

henoch–schönlein purpura (hsp), a common allergic hemorrhagic disease, occurs frequently in children affecting kidney, joint and skin. while interleukin-8 (il-8) plays an important role in inflammation, the association between il-8 gene +781 c/t polymorphism and hsp remains unclear. interleukin-8, an important chemokine related to the initiation and amplification of acute inflammatory responses...

Background: Genetic polymorphism of milk proteins has been associated with composition, manufacture, and traits of milk. Caseins are the most important milk proteins whose genes are strongly linked and inherited as a raceme. κ-casein which is a quantitatively minor constituent of bovine milk is thought to play a critical role in organization, fixation and aggregation of casein micelles and firm...