Nipple fissure is a common problem during breastfeeding. Zizyphus Jujube Fruits is one of the oldest medicinal plants which can heal wounds through its antimicrobial and anti-inflammatory properties. This study aimed to determine the effect of jujube lotion on the recovery of breast fissure. This double-blind clinical trial recruited 100 primiparous lactating women who were randomly divided int...

Introduction: Topical antimicrobials, such as clindamycin, are effective in the treatment of acne and azelaic acid, due to the lack of bacterial resistance, could be a useful alternative in topical treatment of acne. The aim of this study was to compare the effect of topical azelaic acid 20% with clindamycin 1% lotion for the treatment of acne. Method: This randomized clinical trial study was p...

Aims: The aim of this manuscript is to present innovative applications of the BTK model that can potentially contribute additional aspects of safety evaluations for a broader range of products and materials intended for prolonged skin contact. Study Design and Methodology: The basic BTK protocol is one 6-h exposure per day for 4 days. Modification to the basic protocol were made for individual ...

Abstract Background: Red betel leaf (P. crocatum Ruiz & Pav) possesses antibacterial properties, so the prospect is to be developed as a deodorant in lotion dosage forms. Objective: This study was conducted with intention prepare, evaluate, and investigate stability of preparations from ethanolic extract red based on stearic acid. Methods: The maceration method used 70% ethanol solvent obta...

BACKGROUND This was a randomized, assessor-blind, controlled comparison of a soya oil- based medical device shampoo with a medicinal permethrin lotion in an alcohol vehicle for treatment of head louse infestation to generate data suitable for a regulatory submission to achieve reimbursable status for the shampoo product. METHODS We treated 91 children and adults, divided between two sites, on...

OBJECTIVE Staphylococcus aureus dominates the skin microbiota in patients with atopic dermatitis (AD), with bacterial loads correlating with disease severity. The aim of this exploratory study was to investigate the effect of a cosmetic lotion containing heat-treated Lactobacillus johnsonii NCC 533 (HT La1) on S. aureus colonization in AD patients. METHODS This open-label, multicenter study w...

Berbagai alternatif telah dilakukan untuk menghambat populasi nyamuk Aedes aegypti penyebab penyakit demam berdarah, diantaranya penggunaan lotion antinyamuk yang mengandung DEET. Untuk mengurangi resiko dan dampak negatif dari DEET, maka salah satu upaya pemanfaatan minyak atsiri kenanga (Cananga odorata) sebagai repellent atau alami. Penelitian ini bertujuan mengetahui rendemen bunga kenanga,...